Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.340 AlteredExpression disease BEFREE Moreover, electrophoretic mobility shift assay (EMSA) revealed that TA-1 downregulated nuclear localization of NF-κB and its phosphorylation induced by TNF-α and this, allows the suppression of the degradation and phosphorylation of IκB and the inhibition of the phosphorylation of p65 phosphorylation and the p50-p65 heterodimer nuclear translocation, causing attenuation of NF-κB-regulated antiapoptotic (Survivin, Bcl-2, c-IAP1/2, Bcl-xL, Mcl-1, and cFLIP), invasion (ICAM1), metasatsis (MMP-9), and angiogenesis (VEGF) gene expression in KBM5; and finally reporter gene expression. 28968948 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.340 AlteredExpression disease BEFREE Efficient modulation of aberrant vascular endothelial growth factor (VEGF) and its receptor-1 (Flt-1) expressions have become a potential therapeutic strategy for hematologic malignancies including myeloid leukemia. 24183807 2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.340 AlteredExpression disease BEFREE PTEN's regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia. 21360018 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.340 Biomarker disease CTD_human Further investigations revealed that knock-down of AGO2 by custom-made AGO2 siRNA in HEK-293 cells resulted in silencing of the expression of target genes vascular endothelial growth factor A and histone deacetylase 2, which are known to be involved in the development of myeloid leukaemia. 21535412 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.340 AlteredExpression disease BEFREE Further investigations revealed that knock-down of AGO2 by custom-made AGO2 siRNA in HEK-293 cells resulted in silencing of the expression of target genes vascular endothelial growth factor A and histone deacetylase 2, which are known to be involved in the development of myeloid leukaemia. 21535412 2011