Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
0.050 AlteredExpression disease BEFREE Low ABCB1 and high OCT1 levels play a favorable role in the molecular response to imatinib in CML patients in the community clinical practice. 27770655 2016
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
0.050 GeneticVariation disease BEFREE OCT1 genetic variants are associated with long term outcomes in imatinib treated chronic myeloid leukemia patients. 24215657 2014
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
0.050 AlteredExpression disease BEFREE OCT1 mRNA and protein expression were analyzed in leukemic cells from patients with imatinib-naïve CML as well as in cell lines. 24352644 2014
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
0.050 AlteredExpression disease BEFREE Chronic myeloid leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 activity. 20147974 2010
Entrez Id: 5451
Gene Symbol: POU2F1
POU2F1
0.050 AlteredExpression disease BEFREE We recently showed that low OCT-1 activity is a major contributor to suboptimal response in chronic myeloid leukemia (CML) patients treated with imatinib. 18559609 2008