Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease BEFREE Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia. 29227812 2018
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease BEFREE Gene sequencing detected a mutation in DNA methyltransferase 3α, which is relatively rarely identified in CMML and has recently been reported to have an independent prognostic impact on overall survival time. 29731877 2018
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease BEFREE We carried out this study to assess the prognostic impact of DNMT3A mutations on a larger informative cohort of CMML patients (n = 261). 27733013 2017
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease BEFREE First: This is the first report on CMML with double-mutations of DNMT3A and FLT3-ITD. 28102729 2017
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease BEFREE We explored prognostic implications of gene mutations such as DNMT3A, issues related to the classification of AML cases with the NPM1 mutation, and myelodysplasia-related changes arising from chronic myelomonocytic leukemia after a short latency interval. 26071459 2015
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease BEFREE DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells. 24497509 2014
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 Biomarker disease BEFREE Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. 21828135 2011
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
0.370 GeneticVariation disease UNIPROT