Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1
0.040 Biomarker disease BEFREE MP-CMML patients had significantly shorter overall survival (OS; <i>P</i> < .0001; hazard ratio: 0.53, 95% confidence interval: 0.42-0.65) and median duration to acute myeloid leukemia (AML) transformation (<i>P</i> < .0001; 15.2 vs 22.0 months) compared with MDS-CMML patients. 30054307 2018
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1
0.040 GeneticVariation disease BEFREE We conclude that SRSF2 is the most frequently mutated spliceosome gene in CMML but neither it nor SF3B1 or U2AF35 mutations are prognostically relevant. 23335386 2013
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1
0.040 Biomarker disease BEFREE Mutations in SRSF2, U2AF1 and SF3B1 were found in 32%, 13% and 6% of cases of chronic myelomonocytic leukemia, secondary acute myeloid leukemia derived from chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia, respectively. 22773603 2013
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1
0.040 GeneticVariation disease BEFREE Among spliceosome component mutations, those involving SF3B1 are most frequent in myelodysplastic syndromes with ring sideroblasts (MDS-RS; ∼ 75% incidence) and SRSF2 in chronic myelomonocytic leukemia (∼ 28% incidence). 22968464 2012