Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.330 Biomarker disease BEFREE Mutated STAT3 is mainly associated with large granular lymphocytic T-cell leukemia, whereas mutated STAT5B is associated with T-cell prolymphocytic leukemia, T-cell acute lymphoblastic leukemia and γδ T-cell-derived lymphomas. 31817042 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.330 Biomarker disease BEFREE In addition, the STAT3 inhibitor S3I-201 not only induced cell growth arrest and cell death but also activated caspase-3 in MT-2 and HUT-102 cells, indicating that STAT3 may be a therapeutic target for ATL. 24090995 2013
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.330 Biomarker disease CTD_human Evaluation of anti-leukemia effect of resveratrol by modulating STAT3 signaling. 19796711 2010
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.330 Biomarker disease BEFREE To further examine the cause of this signaling pathway deregulation, we measured mRNA and protein expression levels by real-time PCR and Western blots, respectively, of four negative regulators of the IL-2R signaling pathway including src homology 2 (SH2)-containing phosphatase (SHP1), cytokine-inducible (CIS) SH2-containing protein, suppressor of cytokine signaling-1 (SOCS1) and protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) in six HTLV-1 negative and seven HTLV-1 positive T-cell leukemia lines. 14630083 2004