Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 Biomarker disease BEFREE Both p15 and p16 genes were homozygously deleted in 4 of 23 acute/lymphomatous ATL (17%). 7742529 1995
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 Biomarker disease BEFREE Deletions of p15 and/or p16 genes as a poor-prognosis factor in adult T-cell leukemia. 9164185 1997
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 GeneticVariation disease BEFREE Similarly, polymerase chain reaction (PCR) analysis of p16 exon 2 revealed a higher incidence of alteration in acute ATL than in chronic ATL [52.9% (18/34) vs. 26.1% (6/23), respectively; p<0.05]. 10378889 1999
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 GeneticVariation disease BEFREE Homozygous deletions of MTAP and p16 genes were detected respectively in six (20.7%) and eight (27.6%) of 29 ATL samples and in 15 (38.5%) and 23 (59%) of 39 T-ALL samples. 10803528 2000
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 Biomarker disease BEFREE Acute/lymphomatous ATLL has frequent alterations of p15 (20%) and p16 (28-67%), while chronic/smoldering ATLL has fewer abnormalities of p15 (0-13%) and p16 (5-26%). 12040438 2002
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 Biomarker disease BEFREE These results indicate that the presence of p16 gene and p16 mRNA do not necessarily indicate the production of p16 protein in ATLL, and that loss of p16 protein function is involved in progression of ATLL. 12846894 2003
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.070 Biomarker disease BEFREE In the current study, we report for the first time that the aberrations of p16 and p53 are mutually exclusive in ATLL and either of the two events is sufficient for the ATLL progression. 15896902 2006