Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.080 | Biomarker | disease | BEFREE | The primary protein product of the human T-cell leukemia virus type 1 (HTLV-1) env gene, gp61, is cleaved to produce both the exterior (gp46) and the transmembrane (gp21) portions of the HTLV-1 envelope protein. | 2677406 | 1989 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Envelope proteins of human T-cell leukemia virus: expression in Escherichia coli and its application to studies of env gene functions. | 6091139 | 1984 | ||||
|
0.080 | Biomarker | disease | BEFREE | To clarify the genetic risk for ATL, we characterized HLA class I alleles of ATL patients and analyzed the anchor motifs of HTLV-1 peptides binding to HLA class I molecules, using 291 lines of anti-HTLV-1 CD8(+) cytotoxic T lymphocytes (CTLs) generated in vitro with a total of 165 synthetic peptides for HTLV-1 Tax and Env proteins. | 11485622 | 2001 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The human T-cell leukemia viruses (HTLV) are replication-competent retroviruses whose genomes contain gag, pol, and env genes as well as a fourth gene, termed x, which is believed to be the transforming gene of HTLV. | 2990032 | 1985 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We did not find changes in the env gene that correlated with HTLV-I-associated neurological disease vs adult T cell leukemia or with the nervous system vs peripheral blood and lymphoid organs. | 8778566 | 1995 | ||||
|
0.080 | Biomarker | disease | BEFREE | Fresh and cultured leukemia cells from an adult T-cell leukemia (ATL) patient which possessed gag and env gene defective human T-cell leukemia virus type I (HTLV-I) provirus genome were molecularly analyzed. | 1405724 | 1992 | ||||
|
0.080 | Biomarker | disease | BEFREE | Comparison of antigenic sites of the envelope glycoprotein of the Iranian isolate of human T-cell leukemia virus type 1 with different subtypes of the virus. | 16883437 | 2006 | ||||
|
0.080 | Biomarker | disease | BEFREE | Antibodies to the envelope glycoprotein of human T cell leukemia virus type 1 robustly activate cell-mediated cytotoxic responses and directly neutralize viral infectivity at multiple steps of the entry process. | 21646298 | 2011 |