Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 Biomarker disease BEFREE Paradoxically, human thioredoxin (TXN1) was first identified as the adult T cell leukemia-derived factor (ADF), a secreted protein. 29138681 2017
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 Biomarker disease BEFREE A new soluble factor named ADF/ATL-derived factor was also detected in ATL cell lines. 22068231 2011
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 AlteredExpression disease BEFREE All B-CLL cells expressed constitutive Trx at varying but low levels, in contrast to adult T-cell leukemias, which overexpress Trx, as previously reported. 10666220 2000
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 Biomarker disease BEFREE Human thioredoxin (hTRX)/adult T-cell leukemia (ATL)-derived factor (ADF) was originally reported as an interleukin-2 (IL-2) receptor-alpha-inducing factor produced by human T-cell lymphotropic virus-1-positive (HTLV-1+) cell lines. 11228744 1999
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 Biomarker disease BEFREE Adult T cell leukemia derived factor (ADF)/thioredoxin (Trx) is known to be an important intracellular antioxidant involved in a number of redox reactions such as ribonucleotide reductase (RNR) as well as of tyrosinase. 9475178 1998
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 AlteredExpression disease BEFREE Increased expression of human thioredoxin/adult T cell leukemia-derived factor in Sjögren's syndrome. 8639174 1996
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.070 Biomarker disease BEFREE To test the possibility that ADF produced by HTLV-1(+) T cells is involved in the abnormal expression of IL 2-R, we studied the effect of ADF on an HTLV-1(+) IL 2-dependent T cell line (ED) in which the beta-chain gene of the T cell antigen receptor (T beta) was rearranged. 2999237 1985