Additionally, the expression levels of miR-125a-5p were significantly upregulated in patients with HCC in the early and advanced stages of disease, compared with patients with CH or LC (P<0.05).
Liver concentrations of miR-125a-5p were significantly higher in patients with cirrhosis (9.75 ± 4.42 AU) when compared with patients with mild (1.39 ± 0.94, <i>p</i> = 0.0002) or moderate fibrosis (2.43 ± 2.18, <i>p</i> = 0.0006) and were moderately higher in occult than in overt HBV infection (<i>p</i> = 0.09).