Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.330 Biomarker disease CTD_human The antifibrotic potential of a sustained release formulation of a PDGFβ-receptor targeted rho kinase inhibitor. 30682444 2019
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.330 Biomarker disease CTD_human Therapeutic effect of bezafibrate against biliary damage: a study of phospholipid secretion via the PPARalpha-MDR3 pathway. 20040336 2010
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.330 GeneticVariation disease BEFREE Four patients without mutation, including one sibling pair, exhibited histologic features of prominent portal fibrosis leading to advanced biliary cirrhosis that were indistinguishable from the case of MDR3 mutation. 11420418 2001
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.330 Biomarker disease LHGDN Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis. 18671305 2008
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.330 AlteredExpression disease BEFREE Using this method we determined the MDR3 mRNA levels in 52 liver specimens from primary biliary cirrhosis (n=11), chronic hepatitis B (n=5), chronic hepatitis C (n=14), non-cholestatic cirrhosis (n=9) and controls (n=13). 9126799 1997
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		0.500 Biomarker disease RGD Magnetic resonance imaging with hepatospecific contrast agents in cirrhotic rat livers. 15770136 2005
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		0.500 Biomarker disease CTD_human Influence of biliary cirrhosis on the detoxification and elimination of a food derived carcinogen. 15542527 2004
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4 		0.010 AlteredExpression disease LHGDN Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis. 17696930 2007
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.300 Biomarker disease CTD_human Influence of biliary cirrhosis on the detoxification and elimination of a food derived carcinogen. 15542527 2004
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.200 Biomarker disease RGD Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2. 19389807 2009
Entrez Id: 59272
Gene Symbol: ACE2
ACE2 		0.200 Biomarker disease RGD Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis. 17532087 2007
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.200 Biomarker disease RGD Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis. 17532087 2007
Entrez Id: 213
Gene Symbol: ALB
ALB 		0.300 Biomarker disease CTD_human Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: The role of Keap-1/Nrf-2 and P38-MAPK/NF-κB/iNOS signaling pathway. 30026087 2018
Entrez Id: 250
Gene Symbol: ALPP
ALPP 		0.010 Biomarker disease LHGDN Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis. 18752324 2008
Entrez Id: 361
Gene Symbol: AQP4
AQP4 		0.200 Biomarker disease RGD Role of aquaporin-4 in the development of brain oedema in liver failure. 20451280 2010
Entrez Id: 472
Gene Symbol: ATM
ATM 		0.010 AlteredExpression disease LHGDN Activation of ATM signaling pathway is involved in oxidative stress-induced expression of mito-inhibitory p21WAF1/Cip1 in chronic non-suppurative destructive cholangitis in primary biliary cirrhosis: an immunohistochemical study. 18456456 2008
Entrez Id: 648
Gene Symbol: BMI1
BMI1 		0.010 AlteredExpression disease LHGDN Decreased expression of Bmi1 is closely associated with cellular senescence in small bile ducts in primary biliary cirrhosis. 16936260 2006
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		0.010 AlteredExpression disease LHGDN High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis. 15968725 2005
Entrez Id: 858
Gene Symbol: CAV2
CAV2 		0.010 AlteredExpression disease LHGDN High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis. 15968725 2005
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.300 Biomarker disease CTD_human Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-kappaB activation. 12126966 2002
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.200 Biomarker disease RGD Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. 19371232 2009
Entrez Id: 939
Gene Symbol: CD27
CD27 		0.010 AlteredExpression disease LHGDN Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis. 15685542 2005
Entrez Id: 915
Gene Symbol: CD3D
CD3D 		0.300 Biomarker disease CTD_human Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid. 18422935 2008
Entrez Id: 941
Gene Symbol: CD80
CD80 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. 21399635 2011
Entrez Id: 1003
Gene Symbol: CDH5
CDH5 		0.300 Biomarker disease CTD_human Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid. 18422935 2008