Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14 		0.200 Biomarker disease MGD aly/aly mice: a unique model of biliary disease. 9620319 1998
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.510 Biomarker disease RGD Ammonia reduction with ornithine phenylacetate restores brain eNOS activity via the DDAH-ADMA pathway in bile duct-ligated cirrhotic rats. 21903766 2012
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.200 Biomarker disease RGD Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. 19371232 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.200 Therapeutic disease RGD Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis. 24619965 2014
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.010 AlteredExpression disease LHGDN Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice. 16849474 2006
Entrez Id: 939
Gene Symbol: CD27
CD27 		0.010 AlteredExpression disease LHGDN Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis. 15685542 2005
Entrez Id: 250
Gene Symbol: ALPP
ALPP 		0.010 Biomarker disease LHGDN Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis. 18752324 2008
Entrez Id: 2805
Gene Symbol: GOT1
GOT1 		0.010 Biomarker disease LHGDN Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis. 18752324 2008
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.010 Biomarker disease LHGDN Characterisation of TNF-related apoptosis-inducing ligand in peripheral blood in patients with primary biliary cirrhosis. 18385934 2008
Entrez Id: 1629
Gene Symbol: DBT
DBT 		0.010 Biomarker disease LHGDN Characterization of a lipoyl domain-independent B-cell autoepitope on the human branched-chain acyltransferase in primary biliary cirrhosis and overlap syndrome with autoimmune hepatitis. 14768949 2005
Entrez Id: 6522
Gene Symbol: SLC4A2
SLC4A2 		0.300 Biomarker disease CTD_human Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. 18188457 2008
Entrez Id: 1737
Gene Symbol: DLAT
DLAT 		0.020 Biomarker disease LHGDN Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis. 12395322 2002
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.010 AlteredExpression disease LHGDN Damaged interlobular bile ducts in primary biliary cirrhosis show reduced expression of glutathione-S-transferase-pi and aberrant expression of 4-hydroxynonenal. 12127421 2002
Entrez Id: 648
Gene Symbol: BMI1
BMI1 		0.010 AlteredExpression disease LHGDN Decreased expression of Bmi1 is closely associated with cellular senescence in small bile ducts in primary biliary cirrhosis. 16936260 2006
Entrez Id: 7297
Gene Symbol: TYK2
TYK2 		0.300 Biomarker disease CTD_human Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. 22961000 2012
Entrez Id: 1737
Gene Symbol: DLAT
DLAT 		0.020 Biomarker disease LHGDN Differential epitope mapping of antibodies to PDC-E2 in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation and primary biliary cirrhosis. 17068145 2007
Entrez Id: 7033
Gene Symbol: TFF3
TFF3 		0.010 AlteredExpression disease LHGDN Differential expression of intestinal trefoil factor in biliary epithelial cells of primary biliary cirrhosis. 12395334 2002
Entrez Id: 1605
Gene Symbol: DAG1
DAG1 		0.200 Biomarker disease RGD Dystroglycan expression in hepatic stellate cells: role in liver fibrosis. 12177244 2002
Entrez Id: 954
Gene Symbol: ENTPD2
ENTPD2 		0.310 Biomarker disease CTD_human Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis. 15651265 2004
Entrez Id: 954
Gene Symbol: ENTPD2
ENTPD2 		0.310 AlteredExpression disease LHGDN Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis. 15651265 2004
Entrez Id: 8654
Gene Symbol: PDE5A
PDE5A 		0.200 Biomarker disease RGD Effect of chronic administration of sildenafil on sodium retention and on the hemodynamic complications associated with liver cirrhosis in the rat. 17610866 2007
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.510 AlteredExpression disease LHGDN Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis. 12445411 2002
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.010 AlteredExpression disease LHGDN Estrogen receptors in cholangiocytes and the progression of primary biliary cirrhosis. 15645536 2004
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.010 AlteredExpression disease LHGDN Expression and DNA-binding activity of signal transducer and activator of transcription 3 in alcoholic cirrhosis compared to normal liver and primary biliary cirrhosis in humans. 12547716 2003
Entrez Id: 3683
Gene Symbol: ITGAL
ITGAL 		0.010 AlteredExpression disease LHGDN Expression of adhesion molecules on mature cholangiocytes in canal of Hering and bile ductules in wedge biopsy samples of primary biliary cirrhosis. 16038038 2005