| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.380 | Biomarker | group | BEFREE | The carcinoembryonic antigen, glypican‑3 (GPC3), is a putative therapeutic target and diagnostic marker of hepatoma. | 30896845 | 2019 | ||||
|
0.380 | Biomarker | group | BEFREE | The antigen targeting and MRI ability for these four kinds of USPIO probes were studied in the GPC3-expressing murine hepatoma cell line Hepa1-6/GPC3. | 31293339 | 2019 | ||||
|
0.380 | Biomarker | group | BEFREE | Glypican-3 (GPC3) has been widely recognized in the progression of liver tumors for several years. | 29901640 | 2018 | ||||
|
0.380 | Biomarker | group | BEFREE | GPC3, a liver tumor homing peptide, was coated onto the surface of apatinib-loaded NBs through biotin-avidin interactions to target liver cancer HepG2 cells. | 30127626 | 2018 | ||||
|
0.380 | Biomarker | group | BEFREE | We constructed a Plasmodium yoelii 17XNL strain (P.y) expressing murine glypican-3 (GPC3) protein (P.y-GPC3), and examined its therapeutic potency in a murine Hepa1-6-induced hepatoma model that highly expressed GPC3 protein. | 28445973 | 2017 | ||||
|
0.380 | Biomarker | group | BEFREE | Codelivery of sorafenib and GPC3 siRNA with PEI-modified liposomes for hepatoma therapy. | 29106433 | 2017 | ||||
|
0.380 | Biomarker | group | BEFREE | T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice. | 26052074 | 2015 | ||||
|
0.380 | Therapeutic | group | RGD | Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma. | 25449037 | 2015 | ||||
|
0.380 | Biomarker | group | BEFREE | The cell proliferation was significantly inhibited (up to 95.11 %) by shRNA plus anti-cancer drugs, suggesting that GPC-3 gene should be a potential target for promoting hepatoma cell apoptosis and inhibiting metastasis through the Wnt/β-catenin and Hh singling pathways. | 24633918 | 2014 | ||||
|
0.380 | Biomarker | group | HPO |