Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
0.700 CausalMutation disease CLINVAR
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
0.500 SusceptibilityMutation disease CLINVAR
Entrez Id: 6330
Gene Symbol: SCN4B
SCN4B
0.320 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 287
Gene Symbol: ANK2
ANK2
0.170 GeneticVariation disease CLINVAR
Entrez Id: 6640
Gene Symbol: SNTA1
SNTA1
0.160 GeneticVariation disease CLINVAR
Entrez Id: 4607
Gene Symbol: MYBPC3
MYBPC3
0.120 CausalMutation disease CLINVAR
Entrez Id: 10142
Gene Symbol: AKAP9
AKAP9
0.110 GeneticVariation disease CLINVAR
Entrez Id: 1832
Gene Symbol: DSP
DSP
0.100 GeneticVariation disease CLINVAR
Entrez Id: 338653
Gene Symbol: KCNQ1-AS1
KCNQ1-AS1
0.100 GeneticVariation disease CLINVAR
Entrez Id: 51066
Gene Symbol: SSUH2
SSUH2
0.100 GeneticVariation disease CLINVAR
Entrez Id: 253017
Gene Symbol: TECRL
TECRL
0.100 GeneticVariation disease CLINVAR
Entrez Id: 6518
Gene Symbol: SLC2A5
SLC2A5
0.100 GeneticVariation disease CLINVAR
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
0.700 CausalMutation disease CLINVAR Activity-dependent development of spinal cord motor neurons. 1467812 1993
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.060 Biomarker disease BEFREE As no recombination was observed between LQT and H-ras-1, and there is a physiological rationale for its involvement in this disease, ras becomes a candidate for the disease locus. 1673802 1991
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.060 Biomarker disease BEFREE As no obligate recombinants were identified in either this or our previous study, the H-ras-1 protooncogene remains a candidate for the LQT disease gene. 1746560 1991
Entrez Id: 653677
Gene Symbol: SEC1P
SEC1P
0.010 GeneticVariation disease BEFREE We prospectively investigated the clinical characteristics and the long-term course of 3,343 individuals from 328 families in which one or more members were identified as affected with LQTS (QTc greater than 0.44 sec1/2). 1884444 1991
Entrez Id: 784
Gene Symbol: CACNB3
CACNB3
0.010 Biomarker disease BEFREE The determination of the structures of the human CACNL1A2 and CACNLB3 genes should facilitate study of the role of these genes in the development of NIDDM and also other genetic diseases such as long QT syndrome. 7557998 1995
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
0.010 Biomarker disease BEFREE The determination of the structures of the human CACNL1A2 and CACNLB3 genes should facilitate study of the role of these genes in the development of NIDDM and also other genetic diseases such as long QT syndrome. 7557998 1995
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
0.500 Biomarker disease BEFREE Since block of IKr is a known mechanism for drug-induced cardiac arrhythmias, the finding that HERG encodes IKr channels provides a mechanistic link between certain forms of inherited and acquired LQT. 7736582 1995
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
0.500 GeneticVariation disease BEFREE Recently, we demonstrated that mutations in a putative cardiac potassium channel gene, HERG, are responsible for the chromosome 7-linked form of long-QT syndrome, whereas mutations in the cardiac sodium channel gene SCN5A cause the chromosome 3-linked form of this disorder. 7788908 1995
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
0.500 Biomarker disease CTD_human Single strand conformation polymorphism and DNA sequence analyses reveal HERG mutations in six LQT families, including two intragenic deletions, one splice-donor mutation, and three missense mutations. 7889573 1995
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
0.500 CausalMutation disease CLINVAR Single strand conformation polymorphism and DNA sequence analyses reveal HERG mutations in six LQT families, including two intragenic deletions, one splice-donor mutation, and three missense mutations. 7889573 1995
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
0.500 GeneticVariation disease BEFREE Single strand conformation polymorphism and DNA sequence analyses reveal HERG mutations in six LQT families, including two intragenic deletions, one splice-donor mutation, and three missense mutations. 7889573 1995
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
0.700 GeneticVariation disease BEFREE We previously mapped three LQT loci: LQT1 on chromosome 11p15.5, LQT2 on 7q35-36, and LQT3 on 3p21-24. 7889574 1995