Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.060 Biomarker disease BEFREE In conclusion, Nrf2 mediates the protective effects of both Wnt3a/β-catenin and AMPK on lung inflammatory responses during the development of COPD/emphysema. 29659176 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.060 Biomarker disease BEFREE Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease. 28245136 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.060 Biomarker disease BEFREE E-cadherin and β-catenin were reduced in smoke exposed cells as well as in lung tissue sections from patients with COPD. 28642260 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.060 Biomarker disease BEFREE We show that FAM13A may influence COPD susceptibility by promoting β-catenin degradation. 26862784 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.060 AlteredExpression disease BEFREE Stimulation of fibroblasts with TGF-β₁, a growth factor important in COPD pathogenesis, induced WNT-5B, FZD₈, DVL3 and β-catenin mRNA expression. 21980461 2011
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.060 AlteredExpression disease BEFREE Targeting β-catenin-dependent gene transcription may therefore hold promise as a therapeutic intervention in airway remodeling in both asthma and COPD. 21908588 2011