Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.340 | Biomarker | group | CTD_human | Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. | 26132489 | 2015 | ||||
|
0.340 | Biomarker | group | BEFREE | As a novel mechanism of lung tumorigenesis mediated by CYP2A6, we investigated the effects of cotinine on the suppression of apoptosis and promotion of lung tumor growth. | 22687995 | 2012 | ||||
|
0.340 | Biomarker | group | CTD_human | CYP2A6 overexpression in human lung cancers correlates with a high malignant status. | 17549345 | 2007 | ||||
|
0.340 | AlteredExpression | group | LHGDN | CYP2A6 overexpression in human lung cancers correlates with a high malignant status. | 17549345 | 2007 | ||||
|
0.340 | GeneticVariation | group | LHGDN | Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk. | 16176798 | 2005 | ||||
|
0.340 | Biomarker | group | CTD_human | Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk. | 16176798 | 2005 | ||||
|
0.340 | GeneticVariation | group | LHGDN | Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers. | 15308589 | 2004 | ||||
|
0.340 | Biomarker | group | CTD_human | Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. | 12214673 | 2002 | ||||
|
0.340 | Biomarker | group | CTD_human | Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. | 11241319 | 2001 | ||||
|
0.340 | Biomarker | group | CTD_human | CYP2A6 gene deletion reduces susceptibility to lung cancer. | 10441482 | 1999 |