Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker group BEFREE IL-10 and IL-10R were found induced in cells surrounding the lung tumour cells, and IL-10R was mainly expressed on the surface of Foxp-3<sup>+</sup> T-regulatory lymphocytes infiltrating the tumour of these patients where its expression inversely correlated with programmed cell death 1. 29016555 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker group BEFREE IL10 knockout in EGFRL858R and Kras4bG12D mice inhibited the development of lung tumors and decreased the levels of infiltrating M2 macrophages and tumor-promoting Treg lymphocytes. 26956044 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker group BEFREE IL10 induction by cigarette smoking plays a role in smoking-related lung tumor progression. 23749933 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 AlteredExpression group BEFREE IL-10 and CIP2A mRNA levels in lung tumors from patients with lung cancer were determined by real-time reverse transcription PCR. 23743567 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker group BEFREE Interleukin-10 (IL-10) expression has been shown in several studies to correlate with a poorer prognosis in NSCLC; however, the mechanisms by which IL-10 affects lung tumor growth and metastases are unclear. 20034810 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation group LHGDN The involvement of IL-10, IL-6, IFN-gamma, TNF-alpha and TGF-beta gene polymorphisms among Turkish lung cancer patients. 17654453 2008
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 AlteredExpression group LHGDN Macrophage expression of interleukin-10 is a prognostic factor in nonsmall cell lung cancer. 17537769 2007
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation group LHGDN The involvement of genetic polymorphism of IL-10 promoter in non-small cell lung cancer. 16122836 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation group LHGDN TNF-alpha, TNF-beta, IL-6, and IL-10 polymorphisms in patients with lung cancer. 16276011 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 AlteredExpression group LHGDN Interleukin-10 expression is closely correlated with the expression of granulocyte-macrophage colony-stimulating factor in non-small cell lung cancer. 12926133 2003
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker group CTD_human Tnfa null (-/-) mice on a B6 background and B6.129 Il-10(-/-) mice were intercrossed with A/J mice and subjected to urethane carcinogenesis; lung tumor multiplicity was determined 20 weeks later. 14587096 2003
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker group BEFREE Our results indicate that lung tumor-derived PGE2 plays a pivotal role in promoting lymphocyte and macrophage IL-10 induction while simultaneously inhibiting macrophage IL-12 production. 9515807 1998