×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
However, the low PKC levels in summer can still decrease further the low production of IL-2 in T cells of lupus patients augmenting the existing AP-1 defects.
30715676
2019
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
IL233 is more potent than IL-2 and IL-33 either singly or in combination in the treatment of lupus GN.
31103267
2019
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
Suppression of Murine Lupus by CD4+ and CD8+ Treg Cells Induced by T Cell-Targeted Nanoparticles Loaded With Interleukin-2 and Transforming Growth Factor β.
30407752
2019
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus .
28646040
2017
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
AlteredExpression
disease
BEFREE
cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus .
23019580
2012
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
AlteredExpression
disease
BEFREE
Moreover, our results also showed that IFN-γ and IL-2 expression was enhanced in TGP-treated lupus CD4(+) T cells.
22406048
2012
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
AlteredExpression
disease
BEFREE
Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus .
22942433
2012
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
AlteredExpression
disease
BEFREE
The expression of miR-31 was significantly decreased in lupus T cells, and this was positively correlated with the expression of IL-2 .
22736314
2012
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
Our findings establish the genetic association between lupus and IL2 /IL21 with a genome-wide level of significance.
21425124
2011
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
Furthermore, MRL-lpr/lpr mice injected with LiCl or with arginine-rich peptide restored the IL-2 production and reduced the manifestations of lupus .
20506162
2010
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
Biomarker
disease
BEFREE
Defective in vitro IL-2 production in lupus is an early but secondary event paralleling disease activity: evidence from the murine parent-into-F1 model supports staging of IL-2 defects in human lupus .
20001649
2010
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
AlteredExpression
disease
BEFREE
Protein kinase A RI beta subunit deficiency in lupus T lymphocytes: bypassing a block in RI beta translation reconstitutes protein kinase A activity and augments IL-2 production.
11390516
2001
×
Entrez Id:
3558
Gene Symbol:
IL2
IL2
0.100
AlteredExpression
disease
BEFREE
These findings suggest that DLE is associated with type 1 cytokines characterized by the expression of IL-2 and IFN-gamma.
11115160
2000