Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
0.420 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
0.420 PosttranslationalModification group BEFREE The gene encoding the DNA repair enzyme O (6)-methylguanine-DNA methyltransferase (MGMT) is transcriptionally silenced by promoter methylation in several human tumors, including gliomas and systemic lymphomas. 21968944 2012
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
0.420 GeneticVariation group BEFREE Mice doubly deficient for either XRCC4 or DNA ligase IV and p53 invariably develop lymphomas bearing characteristic chromosome translocations with gene amplification. 12150897 2002
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
0.420 Biomarker group HPO