Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 94115
Gene Symbol: CGB8
CGB8
0.010 AlteredExpression disease BEFREE Additionally, PTEN negatively correlated with p53 expression in FL and CGB DLBCL, whereas NF-κB negatively correlated with WWP2 in GCB DLBCL, but positively associated with PTEN in RFH and c-Myc in BL. 30899409 2019
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1
0.010 Biomarker disease BEFREE In the present study, we show that TRA-1-60-expressing cells are a unique population in FL, converge to the conventional stem cell marker Oct3/4 and ALDH1-positive population, and resist current B-lymphoma agents. 30417470 2019
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.010 Biomarker disease BEFREE These include B-lymphocyte proliferation and sustained clonal expansion by HCV-envelope protein stimulation of B-cell receptors, and prolonged HCV-infected B-cell growth by overexpression of an anti-apoptotic BCL-2 oncogene caused by the increased frequency of t(14;18) chromosomal translocations in follicular lymphomas. 31092372 2019
Entrez Id: 9736
Gene Symbol: USP34
USP34
0.010 Biomarker disease BEFREE BCL11A, PAPOLG, PUS10, and USP34) in this amplified locus have not been systematically investigated to date in terms of their role in FL pathogenesis or transformation to tFL. 31410080 2019
Entrez Id: 970
Gene Symbol: CD70
CD70
0.010 Biomarker disease BEFREE Purpose This first-in-human study evaluated SGN-CD70A, an antibody-drug conjugate (ADC) directed against the integral plasma membrane protein CD70 and linked to a pyrrolobenzodiazepine (PBD) dimer, in patients with relapsed or refractory (R/R) CD70-positive non-Hodgkin lymphoma (NHL) including diffuse large B cell lymphoma (DLBCL), mantle cell lymphoma (MCL), and Grade 3b follicular lymphoma (FL3b). 30132271 2019
Entrez Id: 8295
Gene Symbol: TRRAP
TRRAP
0.010 Biomarker disease BEFREE Hence, TRA-1-60-expressing cells in FL are considered to be vigorously intractable against conventional therapeutic agents, which may explain its refractory recurrence. 30417470 2019
Entrez Id: 64895
Gene Symbol: PAPOLG
PAPOLG
0.010 AlteredExpression disease BEFREE Compared with the level in normal B-cells, PAPOLG was significantly overexpressed in FL cases, but expression levels of the other three genes did not show any significant difference. 31410080 2019
Entrez Id: 10013
Gene Symbol: HDAC6
HDAC6
0.010 Biomarker disease BEFREE We first showed that FL is the most sensitive to HDAC6 inhibitor. 30693983 2019
Entrez Id: 6687
Gene Symbol: SPG7
SPG7
0.010 Biomarker disease BEFREE No significant differences in CAR-T cell in vivo expansion/persistence were observed between FL and tFL patients. 31648294 2019
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
0.010 Biomarker disease BEFREE SLC2A1 turned out to represent the hub of a functional network, connecting channels and transporters in FL. 31197180 2019
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
0.010 Biomarker disease BEFREE Rituximab may overcome immune-dormancy in follicular lymphoma in cases with lower intrafollicular T-cell numbers and higher CD56 and CD68 cell counts. 31273513 2019
Entrez Id: 25859
Gene Symbol: PART1
PART1
0.010 Biomarker disease BEFREE Front-line management of non-Hodgkin lymphoma in Australia. Part 1: follicular lymphoma. 30230156 2019
Entrez Id: 653108
Gene Symbol: CXADRP1
CXADRP1
0.010 Biomarker disease BEFREE No significant differences in CAR-T cell in vivo expansion/persistence were observed between FL and tFL patients. 31648294 2019
Entrez Id: 406979
Gene Symbol: MIR19A
MIR19A
0.010 AlteredExpression disease BEFREE The expression of miR‑17‑92 in FL differed significantly from that in GBC, and miR‑19a may have a crucial effect on the OS and EFS of patients with B‑NHL. 31322189 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.010 Biomarker disease BEFREE This study was aimed at evaluating the feasibility, safety, immunologic and clinical responses in patients with follicular lymphoma treated with monocyte-derived dendritic cells generated in the presence of IFNα and GM-CSF (IFN-DC) in combination with low doses of rituximab. 31171545 2019
Entrez Id: 11060
Gene Symbol: WWP2
WWP2
0.010 AlteredExpression disease BEFREE PTEN expression was elevated in GCB DLBCL and BL compared with RFH, and in GCB DLBCL, non-GCB DLBCL and BL than that in FL; WWP2 expression was higher in FL, GCB DLBCL, non-GCB DLBCL and BL compared with RFH; p53 expression increased in non-GCB DLBCL compared with RFH, and in BL compared with RFH, FL or GCB DLBCL; c-Myc expression was higher in GCB DLBCL, non-GCB DLBCL and BL compared with RFH; c-Myc expression was elevated in GCB DLBCL, non-GCB DLBCL and BL compared with FL. 30899409 2019
Entrez Id: 407
Gene Symbol: ARR3
ARR3
0.010 Biomarker disease BEFREE No significant differences in CAR-T cell in vivo expansion/persistence were observed between FL and tFL patients. 31648294 2019
Entrez Id: 2033
Gene Symbol: EP300
EP300
0.010 Biomarker disease BEFREE These data provide proof-of-principle for the clinical development of EP300-specific inhibitors in FL and DLBCL. 31519498 2019
Entrez Id: 1082
Gene Symbol: CGB3
CGB3
0.010 AlteredExpression disease BEFREE Additionally, PTEN negatively correlated with p53 expression in FL and CGB DLBCL, whereas NF-κB negatively correlated with WWP2 in GCB DLBCL, but positively associated with PTEN in RFH and c-Myc in BL. 30899409 2019
Entrez Id: 93659
Gene Symbol: CGB5
CGB5
0.010 AlteredExpression disease BEFREE Additionally, PTEN negatively correlated with p53 expression in FL and CGB DLBCL, whereas NF-κB negatively correlated with WWP2 in GCB DLBCL, but positively associated with PTEN in RFH and c-Myc in BL. 30899409 2019
Entrez Id: 846
Gene Symbol: CASR
CASR
0.010 Biomarker disease BEFREE No significant differences in CAR-T cell in vivo expansion/persistence were observed between FL and tFL patients. 31648294 2019
Entrez Id: 28424
Gene Symbol: IGHV3-48
IGHV3-48
0.010 Biomarker disease BEFREE IGHV3-48 was overrepresented in cases of tFL (19%) compared with non-transformed FL at 5 years (5%, P = 0.05). 31209206 2019
Entrez Id: 1114
Gene Symbol: CHGB
CHGB
0.010 AlteredExpression disease BEFREE Additionally, PTEN negatively correlated with p53 expression in FL and CGB DLBCL, whereas NF-κB negatively correlated with WWP2 in GCB DLBCL, but positively associated with PTEN in RFH and c-Myc in BL. 30899409 2019
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
0.010 GeneticVariation disease BEFREE The <i>HLA-A*0201∼C*0602∼B*1302∼DRB1*0701∼DQB1*0201</i> haplotype was significantly associated with follicular lymphoma (FL) risk among Caucasians. 31215275 2019
Entrez Id: 10206
Gene Symbol: TRIM13
TRIM13
0.010 Biomarker disease BEFREE No significant differences in CAR-T cell in vivo expansion/persistence were observed between FL and tFL patients. 31648294 2019