Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
0.600 CausalMutation disease CGI
Entrez Id: 8915
Gene Symbol: BCL10
BCL10
0.420 CausalMutation disease CLINVAR
Entrez Id: 8915
Gene Symbol: BCL10
BCL10
0.420 CausalMutation disease CGI
Entrez Id: 8764
Gene Symbol: TNFRSF14
TNFRSF14
0.370 CausalMutation disease CGI
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 GeneticVariation disease BEFREE The gene coding for these transcript (the bcl-2 gene) seems to be interrupted in most cases of follicular lymphomas carrying the t(14;18) chromosomal translocation. 3874430 1985
Entrez Id: 613
Gene Symbol: BCR
BCR
0.090 GeneticVariation disease BEFREE Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. 2865728 1985
Entrez Id: 4311
Gene Symbol: MME
MME
0.100 Biomarker disease BEFREE All cases showed expression of the B lineage markers T015, B1, and 4G7, and HLA-DR. CALLA was present in all but 1 case, similar to that reported for follicular lymphomas, and much higher than reported for diffuse large cell lymphoma. 3521302 1986
Entrez Id: 613
Gene Symbol: BCR
BCR
0.090 Biomarker disease BEFREE Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas. 3014037 1986
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE c-yes and bcl-2 genes located on 18q21.3 in a follicular lymphoma cell line carrying a t(14;18) chromosomal translocation. 3034807 1987
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 GeneticVariation disease BEFREE DNA rearrangements in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene. 3547408 1987
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE Characterization of the protein product of bcl-2, the gene involved in human follicular lymphoma. 3325884 1987
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 GeneticVariation disease BEFREE In this patient's leukemic cells, the breakpoint of the t(14;18) translocation occurred in the major breakpoint-cluster region of the BCL2 gene and became linked to the JH4 joining-region gene segment of the immunoglobulin heavy-chain locus on the 14q+ chromosome as previously observed in follicular lymphoma. 3186743 1988
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE In the present study, bcl-2 was rearranged in 30% (11 of 37) of follicular lymphomas and 19% (11 of 58) of diffuse lymphomas of follicle center cell lineage. 2965608 1988
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease CTD_human Immunoreactive bcl-2 protein was observed in the neoplastic cells in almost all the follicular lymphomas, whereas no bcl-2 protein was detected in follicles affected by non-neoplastic processes or in normal lymphoid tissue. 3287162 1988
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE Immunoreactive bcl-2 protein was observed in the neoplastic cells in almost all the follicular lymphomas, whereas no bcl-2 protein was detected in follicles affected by non-neoplastic processes or in normal lymphoid tissue. 3287162 1988
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 GeneticVariation disease BEFREE To detect occult lymphoma, the polymerase chain reaction (PCR) technique was used to amplify joined bcl-2/JH DNA sequences at the juncture of the t(14:18) translocation in follicular lymphoma. 3140914 1988
Entrez Id: 613
Gene Symbol: BCR
BCR
0.090 GeneticVariation disease BEFREE In this patient's leukemic cells, the breakpoint of the t(14;18) translocation occurred in the major breakpoint-cluster region of the BCL2 gene and became linked to the JH4 joining-region gene segment of the immunoglobulin heavy-chain locus on the 14q+ chromosome as previously observed in follicular lymphoma. 3186743 1988
Entrez Id: 1791
Gene Symbol: DNTT
DNTT
0.010 Biomarker disease BEFREE The terminal deoxynucleotidyltransferase-positive phenotype of the patient's leukemic cells further suggests that the pre-B-cell leukemia was derived from a pre-B cell carrying a t(14;18) translocation in the original follicular lymphoma. 3186743 1988
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 GeneticVariation disease BEFREE Detection of chromosomal translocation t(14;18) within the minor cluster region of bcl-2 by polymerase chain reaction and direct genomic sequencing of the enzymatically amplified DNA in follicular lymphomas. 2713505 1989
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE Twenty-three patients with B-cell non-immunoblastic lymphoma or follicular lymphoma who had a bcl-2 oncogene rearrangement had a poorer response to therapy (7 of 23 with complete remission) than the patients without bcl-2 rearrangement (21 of 26 with complete remission). 2648153 1989
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE Involvement of bcl-2 gene in Japanese follicular lymphoma. 2644990 1989
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE Molecular analysis showed that BCL2 was rearranged in the major breakpoint cluster region and had joined into the immunoglobulin heavy chain gene as in follicular lymphoma. 2682663 1989
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 Biomarker disease BEFREE It was also suggested that this case had originated from a more differentiated B cell than most follicular lymphomas with bcl-2-Ig H recombination. 2511176 1989
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.600 AlteredExpression disease BEFREE The growth advantage of EBV-infected B cells by overproduction of the BCL-2 protein suggests the direct involvement of the BCL-2 gene product in the pathogenesis of follicular lymphoma. 2538824 1989
Entrez Id: 613
Gene Symbol: BCR
BCR
0.090 Biomarker disease BEFREE Molecular analysis showed that BCL2 was rearranged in the major breakpoint cluster region and had joined into the immunoglobulin heavy chain gene as in follicular lymphoma. 2682663 1989