|
HLA-DRB1
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
The <i>HLA-A*0201∼C*0602∼B*1302∼DRB1*0701∼DQB1*0201</i> haplotype was significantly associated with follicular lymphoma (FL) risk among Caucasians.
|
31215275 |
2019 |
|
HLA-DRB1
|
0.470 |
Biomarker
|
disease |
BEFREE |
We hypothesized that amino acids in HLA-antigen D-related β1 subunit (DRB1) interact with smoking in FL risk, as shown for rheumatoid arthritis.
|
28369180 |
2017 |
|
HLA-DRB1
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
We confirmed that FL-protective rs2647012-linked variants, in high linkage disequilibrium with the extended haplotype DRB1*15:01-DQA1*01:02-DQB1*06:02, correlate with increased HLA-DQB1 expression.
|
24304973 |
2014 |
|
HLA-DRB1
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk.
|
23791106 |
2013 |
|
HLA-DRB1
|
0.470 |
SusceptibilityMutation
|
disease |
ORPHANET |
Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk.
|
23791106 |
2013 |
|
HLA-DRB1
|
0.470 |
GeneticVariation
|
disease |
GWASDB |
A meta-analysis of genome-wide association studies of follicular lymphoma.
|
23025665 |
2012 |
|
HLA-DRB1
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
Extended haplotypes DRB1*01:01-DQA1*01:01-DQB1*05:01 (OR = 2.01, 95% CI = 1.22-3.38) and DRB1*15-DQA1*01-DQB1*06 (OR = 0.55, 95% CI = 0.36-0.82) also influenced FL risk.
|
22296171 |
2012 |
|
HLA-DRB1
|
0.470 |
GeneticVariation
|
disease |
BEFREE |
In a recent genome-wide association study of follicular lymphoma (FL), we identified novel risk alleles on chromosome 6p21.33 that appeared to be part of an extended haplotype including HLA-DRB1*0101, DQA1*0101, and DQB1*0501.
|
21133715 |
2011 |
|
HLA-DRB1
|
0.470 |
Biomarker
|
disease |
BEFREE |
Statistically significant associations between HLA and NHL subtypes include HLA-DRB1*0101 for follicular lymphoma (odds ratio [OR] = 2.14, P < .001), HLA-DRB1*0401 for diffuse large B-cell lymphoma (DLBCL; OR = 0.45, P = .006), and HLA-DRB1*13 and follicular lymphoma (OR = 0.48, P = .008).
|
20385791 |
2010 |