| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | group | BEFREE | Autoimmune lymphoproliferative syndrome (ALPS) with FAS mutation (ALPS-FAS) is a nonmalignant, noninfectious, lymphoproliferative disease with autoimmunity. | 29686686 | 2018 | ||||
|
0.070 | Biomarker | group | BEFREE | Identification of a genetic defect in the FAS-mediated apoptosis pathway confirms that the lymphoproliferative disease in BSH cats fulfills the diagnostic criteria for ALPS in humans. | 27770190 | 2017 | ||||
|
0.070 | GeneticVariation | group | BEFREE | This report confirms previous observations that lymphoproliferative disorder could be associated not only with CD95 and/or CD178 mutations, but also with dysfunction of other components of apoptosis induction pathway. | 15492869 | 2004 | ||||
|
0.070 | GeneticVariation | group | LHGDN | This report confirms previous observations that lymphoproliferative disorder could be associated not only with CD95 and/or CD178 mutations, but also with dysfunction of other components of apoptosis induction pathway. | 15492869 | 2004 | ||||
|
0.070 | GeneticVariation | group | BEFREE | We have recently identified an ALPS-like clinical pattern (named autoimmune lymphoproliferative disease [ALD]) in patients with decreased Fas function, but no Fas gene mutation. | 10807785 | 2000 | ||||
|
0.070 | Biomarker | group | BEFREE | Deficiency of CD95 (Apo-1/Fas)-mediated apoptosis has recently been found in some autoimmune lymphoproliferative disorders due to inherited mutations of the CD95 gene. | 10487849 | 1999 | ||||
|
0.070 | Biomarker | group | BEFREE | While thymocytes from either line of mice were completely protected from CD95-dependent cytotoxicity, neither transgene afforded protection from apoptosis induced during thymocyte selection and neither led to the lymphoproliferative disorders associated with deficiencies in CD95. | 9586634 | 1998 | ||||
|
0.070 | GeneticVariation | group | BEFREE | Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder. | 9533447 | 1998 |