Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Improving CD20 antibody therapy: obinutuzumab in lymphoproliferative disorders. 30668192 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE This case illustrates a rare entity of plasma cell myeloma, where the entire plasma cell population exhibited lymphoid morphology, negativity for CD138, positivity for CD20 and cyclin D1, and positive fluorescence in situ hybridisation for t(11;14) and del(17 p), mimicking a mature B-cell lymphoproliferative disorder, in particular mantle cell lymphoma. 31791993 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Epstein-Barr Virus-Associated Post-Transplantation Lymphoproliferative Disease in Patients Who Received Anti-CD20 after Hematopoietic Stem Cell Transplantation. 31421238 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Rituximab is indicated for CD20+ posttransplant lymphoproliferative disorder. 28614191 2018
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Since its initial approval in 1997, rituximab has revolutionized the treatment of CD20-positive lymphoproliferative disorders. 30483893 2018
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE More importantly, only 1 direct comparison among the anti-CD20 agents was identified, emphasizing the need for head-to-head randomized controlled trials of these drugs to inform clinical decision-making for patients with relapsed or refractory B-cell lymphoproliferative disorders. 29934061 2018
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 AlteredExpression group BEFREE We present an unusual case of indolent T-cell lymphoproliferative disorder with aberrant CD20 expression, Recognition of this unusual immunophenotype of indolent T-cell LPD of GI helps to eschew misdiagnosis of B-cell and other high grade lymphomas and inappropriate aggressive treatment. 30342536 2018
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE The next-generation CD20 antibody obinutuzumab represents an addition to the drug armamentarium used for the therapeutic management of patients with LPDs. 28893099 2017
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Purpose The Sequential Treatment of CD20-Positive Posttransplant Lymphoproliferative Disorder (PTLD-1) trial ( ClinicalTrials.gov identifier, NCT01458548) established sequential treatment with four cycles of rituximab followed by four cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy as a standard in the management of post-transplant lymphoproliferative disorder (PTLD) and identified response to rituximab induction as a prognostic factor for overall survival. 27992268 2017
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Fcγ-receptor IIIA polymorphism p.158F has no negative predictive impact on rituximab therapy with and without sequential chemotherapy in CD20-positive posttransplant lymphoproliferative disorder. 24741582 2014
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE We hypothesized that detection of phospho-ERK (pERK) in tissue sections may be a useful marker for diagnosis of HCL. pERK/CD20 double immunostaining was performed on 90 formalin-fixed bone marrow trephine samples affected with small B-cell lymphoproliferative disorders, including 28 cases of HCL. pERK staining was observed in all 28 cases of HCL and in 1 of 62 cases of non-HCL B-cell lymphoproliferative disorders. 23211289 2013
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Eight patients obtained spontaneous remission and in the remaining 3 patients 2 with long-lasting PRCA were successfully treated with plasma exchange with donor-type plasma replacement and the other one who was also complicated by EBV-associated lymphoproliferative disorder (EBV-PTLD) responded rapidly to anti-CD20 monoclonal antibody and achieved complete resolution of clinical finding and symptom of both EBV-PTLD and PRCA. 17454192 2007
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Quantification of EBV DNA load in asymptomatic individuals who are at risk is a useful (although not entirely predictive) indicator of progression to EBV-LPD and guide for preemptive treatment with CD20 antibodies. 16705581 2006
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Rituximab, an anti-CD20 monoclonal antibody used to treat B cell lymphoproliferative disorders and autoimmune diseases, kills cells through complement dependent cytotoxicity, antibody-dependent cellular toxicity and apoptosis. 15160958 2004
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 AlteredExpression group BEFREE Tumor origin and CD20 expression in posttransplant lymphoproliferative disorder occurring in solid organ transplant recipients: implications for immune-based therapy. 14508361 2003
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Because the humanized anti-CD20 antibody, rituximab, has antitumor activity in patients with PTLD and stimulates apoptosis in some lymphoid cell lines, we sought to determine whether Bcl-2 antisense treatment potentiates the antitumor effects of rituximab in EBV-associated lymphoproliferative disease in vitro and in vivo. 12738752 2003
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 Biomarker group BEFREE Anti-CD20 monoclonal antibody treatment of Epstein-Barr virus-induced intrahepatic lymphoproliferative disorder following liver transplantation. 12664216 2003
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.100 AlteredExpression group BEFREE CD-20 expression in post-transplant lymphoproliferative disorders: treatment with rituximab. 10996837 2000