| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | The MHC class I system, however, may play an important role, as particular bonobo allotypes show functional similarities to HLA-B*53/B*78, which are considered to confer protection against malaria in humans. | 30126696 | 2018 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | In this study, our objective was to assess whether pathogen-driven selection associated with malaria contributed to shape the HLA-B genetic landscape of Africa. | 28950417 | 2017 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Because of the prevalence of malaria in the Ga-Adangbe and previous associations of cerebral malaria with HLA-B*53:01 and KIR, Plasmodium falciparum is a candidate pathogen. | 24204327 | 2013 | ||||
|
0.070 | Biomarker | disease | BEFREE | Further, HLA-B*35:01 and -B*53:01 exhibited opposite effects on the incidence of malaria with significant parasitemia. | 21756958 | 2011 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Limited experiments with EBV epitope peptides (restricted through the HLA-B 3501 and HLA-B 5301 alleles) also suggested an impairment of virus-specific CD8(+) T cell function in children with malaria, but only during acute disease. | 19032105 | 2009 | ||||
|
0.070 | GeneticVariation | disease | LHGDN | Evolution and selection of human leukocyte antigen alleles by Plasmodium falciparum infection. | 18824049 | 2008 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Thus, further study with a larger sample size must be conducted to obtain conclusive evidence of the association of these HLA-B and DRB1 alleles with the severity of malaria in Thailand. | 15728986 | 2005 | ||||
|
0.070 | GeneticVariation | disease | LHGDN | Thus, further study with a larger sample size must be conducted to obtain conclusive evidence of the association of these HLA-B and DRB1 alleles with the severity of malaria in Thailand. | 15728986 | 2005 |