| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection. | 30006528 | 2018 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Further, diplotype (MIF-794CATT and rs34383331T > A) 5 T confers protection to severe malaria (OR = 0.55, p = 0.002) while 6A (OR = 3.07, p = 0.001) increases malaria risk. | 24066864 | 2013 | ||||
|
0.070 | Biomarker | disease | BEFREE | Although there has been some progress in recent studies, the biological function of the malaria parasite-derived MIF is still far from clear. | 18262164 | 2008 | ||||
|
0.070 | Biomarker | disease | BEFREE | Higher production of peripheral blood macrophage migration inhibitory factor in healthy children with a history of mild malaria relative to children with a history of severe malaria. | 17556607 | 2007 | ||||
|
0.070 | Biomarker | disease | BEFREE | These results indicate that PfMIF is released during blood-stage malaria and potentially modulates the function of monocytes during acute P. falciparum infection. | 17299722 | 2007 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | As the role of genetic variation in the MIF gene in conditioning malaria disease outcomes is largely unexplored, the relationship between a G to C transition at MIF -173 and susceptibility to high-density parasitemia (HDP) and severe malarial anemia (SMA) was examined in Kenyan children (aged 3-36 months; n=477) in a holoendemic Plasmodium falciparum transmission region. | 16929348 | 2006 | ||||
|
0.070 | AlteredExpression | disease | LHGDN | Immunity to placental malaria. IV. Placental malaria is associated with up-regulation of macrophage migration inhibitory factor in intervillous blood. | 12402212 | 2002 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Immunity to placental malaria. IV. Placental malaria is associated with up-regulation of macrophage migration inhibitory factor in intervillous blood. | 12402212 | 2002 |