Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 53342
Gene Symbol: IL17D
IL17D
0.010 Biomarker disease BEFREE Because there is a particular link of IL-23/Th17 axis in the development of cancer and IL-27 has been considered a potential treatment for cancer, we evaluated the gastric and serum concentrations of IL-27 in two mutually exclusive Helicobacter pylori-associated diseases, gastric cancer (GC) and duodenal ulcer (DU). 31702083 2020
Entrez Id: 100506757
Gene Symbol: LINC00629
LINC00629
0.010 Biomarker disease BEFREE Here, this study identified the potential role of a novel lncRNA, LINC00629 in gastric cancer and to elucidate the underlying mechanism. 31674022 2020
Entrez Id: 1902
Gene Symbol: LPAR1
LPAR1
0.010 Biomarker disease BEFREE We also found that miR-501-5p could directly target lysophosphatidic acid receptor 1 (LPAR1) and negatively regulate LPAR1 expression in GC cell lines by performing dual-luciferase reporter gene assay and Western blot analysis. 31746031 2020
Entrez Id: 100126321
Gene Symbol: MIR922
MIR922
0.010 Biomarker disease BEFREE In conclusion, miR-922 may have potential for diagnosis of GC. 31709719 2020
Entrez Id: 56005
Gene Symbol: MYDGF
MYDGF
0.010 Biomarker disease BEFREE Because there is a particular link of IL-23/Th17 axis in the development of cancer and IL-27 has been considered a potential treatment for cancer, we evaluated the gastric and serum concentrations of IL-27 in two mutually exclusive Helicobacter pylori-associated diseases, gastric cancer (GC) and duodenal ulcer (DU). 31702083 2020
Entrez Id: 11148
Gene Symbol: HHLA2
HHLA2
0.010 AlteredExpression disease BEFREE In conclusion, HHLA2 protein overexpression in gastric cancer tissue is potential risk factor for malignant status and poor prognosis. 31552567 2020
Entrez Id: 58516
Gene Symbol: SINHCAF
SINHCAF
0.010 Biomarker disease BEFREE Thus, our study provides evidence that FAM60A act as a carcinogen and suggests that H. pylori-induced upregulation of FAM60A may contribute to the development of gastric cancer. 31727367 2020
Entrez Id: 847
Gene Symbol: CAT
CAT
0.010 Biomarker disease BEFREE Further, results revealed that AGE alleviated the oxidative stress as evidenced by the stomach antioxidant enzymes (SOD, catalase, GPx, and GR), markers of oxidative stress (TRx, GRx) and Gastrin, a specific marker for gastric cancer and a decreased level of pro-inflammatory markers (NF-kB, TNF-α, IL-6, PGE<sub>2</sub>) which was further confirmed by histopathological analysis. 31155951 2020
Entrez Id: 5932
Gene Symbol: RBBP8
RBBP8
0.010 AlteredExpression disease BEFREE Through immunohistochemistry staining of paired gastric cancer (GC) tissues, adjacent high-grade intraepithelial neoplasia (HGIEN) tissues, and non-cancerous tissues, we found RBBP8 expression was upregulated in both HGIEN and GC tissues. 31636387 2020
Entrez Id: 105379054
Gene Symbol: VCAN-AS1
VCAN-AS1
0.010 Biomarker disease BEFREE More important, we discovered that VCAN-AS1 expression was negatively correlated with wild-type p53 levels in GC tissues and that p53 was negatively modulated by VCAN-AS1 in GC cells. 31637706 2020
Entrez Id: 284836
Gene Symbol: LINC00319
LINC00319
0.010 Biomarker disease BEFREE Therefore, this study is to clarify the mechanism by which LINC00319 sponges <i>miR-335-5p</i> to influence development of GC. 31433213 2020
Entrez Id: 729082
Gene Symbol: OIP5-AS1
OIP5-AS1
0.010 AlteredExpression disease BEFREE The heightened level of OIP5-AS1 was detected in GC cell lines. 31219209 2020
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.010 Biomarker disease BEFREE We show that wild-type <i>IDH1</i> is essential for GC cell survival, and that certain GC cells can be targeted by IDH1 inhibitors. 31068366 2020
Entrez Id: 361
Gene Symbol: AQP4
AQP4
0.010 Biomarker disease BEFREE Either downregulating miR-196b-5p or upregulating AQP4 could restrain the development of gastric cancer in vitro. 31674022 2020
Entrez Id: 23098
Gene Symbol: SARM1
SARM1
0.010 Biomarker disease BEFREE The secreted Nodal further activated Samd2/3/Akt signals to trigger the GC progression. 31733068 2020
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
0.010 Biomarker disease BEFREE The function of the DLX6-AS1/miR-204-5p/OCT1 axis in GC proliferation was clarified by rescue assays. 31463827 2020
Entrez Id: 51203
Gene Symbol: NUSAP1
NUSAP1
0.010 AlteredExpression disease BEFREE SIGNIFICANCE OF THE STUDY: Our results firstly illuminated that NUSAP1 expression was significantly upregulated in GC tissues and predicted poor FPS. 31710389 2020
Entrez Id: 100126314
Gene Symbol: MIR877
MIR877
0.010 AlteredExpression disease BEFREE Circular RNA circ-RanGAP1 regulates VEGFA expression by targeting miR-877-3p to facilitate gastric cancer invasion and metastasis. 31811909 2020
Entrez Id: 54737
Gene Symbol: MPHOSPH8
MPHOSPH8
0.010 AlteredExpression disease BEFREE Furthermore, MPP8 overexpression in tumor tissues was marginally associated with a poor prognosis, with a significant relationship between MPP8 overexpression and prognosis among patients with poorly differentiated gastric cancer. 31692032 2020
Entrez Id: 246778
Gene Symbol: IL27
IL27
0.010 Biomarker disease BEFREE Because there is a particular link of IL-23/Th17 axis in the development of cancer and IL-27 has been considered a potential treatment for cancer, we evaluated the gastric and serum concentrations of IL-27 in two mutually exclusive Helicobacter pylori-associated diseases, gastric cancer (GC) and duodenal ulcer (DU). 31702083 2020
Entrez Id: 114041
Gene Symbol: B3GALT5-AS1
B3GALT5-AS1
0.010 Biomarker disease BEFREE Our study suggested that serum B3GALT5-AS1 may be employed as an ideal biomarker for early screening of GC. 31338903 2020
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4
0.010 Biomarker disease BEFREE Therefore, CYP3A4 may be biomarkers to predict progression of CAG and poor prognosis of gastric cancer. 31441961 2020
Entrez Id: 8836
Gene Symbol: GGH
GGH
0.010 Biomarker disease BEFREE High gamma-glutamyl hydrolase and low folylpolyglutamate synthetase expression as prognostic biomarkers in patients with locally advanced gastric cancer who were administrated postoperative adjuvant chemotherapy with S-1. 31754833 2020
Entrez Id: 574412
Gene Symbol: MIR452
MIR452
0.010 Biomarker disease BEFREE However, the role and mechanism of miR-452 in gastric cancer is still unclear. 31734055 2020
Entrez Id: 945
Gene Symbol: CD33
CD33
0.010 Biomarker disease BEFREE The prognostic impact of recruited CD33+ immature myeloid-derived cells were clinicopathologically analyzed in curatively resected stage II and III GC. 31472311 2020