Gene: CHEK2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 Biomarker disease HPO
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 GeneticVariation disease BEFREE Thus, it was indicated that germline CHK2 mutations do not contribute to the familial clustering of gastric cancer. 11011113 2000
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 Biomarker disease CTD_human A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients. 21364753 2011
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 GeneticVariation disease BEFREE CHEK2 mutations predispose to gastric cancer, in particular to young-onset cases. 23296741 2013
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 Biomarker disease BEFREE The most significant gene in ESCC was CHEK2 (P = 2.00 × 10(-6)) and in GC was CLK2 (P = 3.02 × 10(-4)). 23504502 2013
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 Biomarker disease BEFREE Results of the overexpression and knockdown studies, showed that Chk1 but not Chk2 regulated the DADS-induced G2/M arrest of MGC803 cells. 25176258 2014
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 GeneticVariation disease BEFREE These results suggested that there was a correlation between mutation of the CHEK2 gene and gastric cancer, and provided an experimental basis for antitumor drug investigation and development according to its mutation target. 29067458 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.460 Biomarker disease BEFREE Thus, the expression and phosphorylation levels of KU70, ILF2, CHK1 and CHK2 were examined by immunohistochemistry in 42 cases of gastric cancer. 29328366 2018