Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5649
Gene Symbol: RELN
RELN
0.300 Biomarker disease CTD_human GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum. 15560956 2005
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
0.300 Biomarker disease CTD_human GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum. 15560956 2005
Entrez Id: 6285
Gene Symbol: S100B
S100B
0.500 Biomarker disease RGD Increased cerebrospinal fluid levels of S100B protein in rat model of mania induced by ouabain. 15581912 2004
Entrez Id: 6285
Gene Symbol: S100B
S100B
0.500 Biomarker disease CTD_human Increased cerebrospinal fluid levels of S100B protein in rat model of mania induced by ouabain. 15581912 2004
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.300 Biomarker disease CTD_human Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia. 15845098 2005
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.300 Biomarker disease CTD_human Serotonin transporter linked promoter (polymorphism) in the serotonin transporter gene may be associated with antidepressant-induced mania in bipolar disorder. 16395126 2006
Entrez Id: 6526
Gene Symbol: SLC5A3
SLC5A3
0.300 Biomarker disease CTD_human Sodium-myo-inositol co-transporter (SMIT-1) mRNA is increased in neutrophils of patients with bipolar 1 disorder and down-regulated under treatment with mood stabilizers. 16420717 2007
Entrez Id: 6285
Gene Symbol: S100B
S100B
0.500 Biomarker disease CTD_human Regionally specific changes in levels of cortical S100beta in bipolar 1 disorder but not schizophrenia. 16476148 2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.300 Biomarker disease CTD_human Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. 17074966 2007
Entrez Id: 4200
Gene Symbol: ME2
ME2
0.310 Biomarker disease PSYGENET The present study suggests that genetic variation in or near the ME2 gene is associated with both psychotic and manic disorders, including schizophrenia and bipolar disorder. 17258816 2007
Entrez Id: 4200
Gene Symbol: ME2
ME2
0.310 GeneticVariation disease BEFREE The present study suggests that genetic variation in or near the ME2 gene is associated with both psychotic and manic disorders, including schizophrenia and bipolar disorder. 17258816 2007
Entrez Id: 84628
Gene Symbol: NTNG2
NTNG2
0.300 Biomarker disease CTD_human Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder. 17507910 2008
Entrez Id: 22854
Gene Symbol: NTNG1
NTNG1
0.300 Biomarker disease CTD_human Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder. 17507910 2008
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.300 Biomarker disease CTD_human Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse? 17659342 2007
Entrez Id: 2898
Gene Symbol: GRIK2
GRIK2
0.300 Biomarker disease CTD_human Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. 18332879 2008
Entrez Id: 5142
Gene Symbol: PDE4B
PDE4B
0.300 Biomarker disease CTD_human PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia. 18394866 2008
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.300 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 288
Gene Symbol: ANK3
ANK3
0.300 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 4729
Gene Symbol: NDUFV2
NDUFV2
0.300 Biomarker disease CTD_human Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia. 19135101 2009
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker disease CTD_human Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder. 19153942 2009
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
0.300 Biomarker disease CTD_human NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD. 19204064 2010
Entrez Id: 6671
Gene Symbol: SP4
SP4
0.300 Biomarker disease CTD_human Transcription factor SP4 is a susceptibility gene for bipolar disorder. 19401786 2009
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010