Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | We aimed to investigate the role of YAP1 gene in the MB SHH cell line DAOY and evaluate cell proliferation, doubling time and 3D spheroids invasion and its consequence on CTGF regulation. | 31073205 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma. | 31541170 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In immunohistochemistry assays, anti-GAB1 antibody expression is positive in tumors showing SHH pathway activation or PTCH mutation, while positive immunoexpression for YAP1 antibody can be only found in WNT-activated and SHH-activated MDB. | 29582169 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Sixty-five MB cases were molecularly stratified using immunohistochemical markers (YAP1, GAB1, β-catenin). | 29412177 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | The primary data suggested YAP1 as a potential driver for the metastasis of medulloblastoma. | 28363815 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | TEAD4's co-activator, YAP1, and the downstream targets, MYC and CCND1, were also found to be upregulated in AT/RT when compared to medulloblastoma. | 27966820 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Regardless of the molecular subgroup of the primary tumor, all six patient-derived medulloblastoma cell lines exhibited a uniform phenotype: immunofluorescence showed the nuclear localization of YAP1, accompanied by strong cytoplasmic positivity for β-catenin and filamin A, as well as weak positivity for GAB1. | 28231263 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | β-catenin, GAB1 and YAP1 were the only IHC markers of utility in classification of MBs into three subgroups viz. | 26222673 | 2016 |