Gene: PLK1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 Biomarker disease BEFREE Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma. 30611741 2019
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 Biomarker disease BEFREE Further, downstream targets of FOXM1 such as PLK1 and cyclin B1 were significantly reduced thus affecting the cell cycle progression in medulloblastoma cell lines. 31541075 2019
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 AlteredExpression disease BEFREE RT-qPCR analysis revealed increased levels of PLK1-4 in all cell lines and in most MB samples, while PLK5 was found underexpressed. 28283778 2017
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 Biomarker disease BEFREE Polo-Like Kinase 1 Pharmacological Inhibition as Monotherapy or in Combination: Comparative Effects of Polo-Like Kinase 1 Inhibition in Medulloblastoma Cells. 28270075 2017
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 Biomarker disease BEFREE PLK1 inhibition prevented medulloblastoma cell proliferation, self-renewal, cell-cycle progression, and induced apoptosis. 24019381 2013
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 Biomarker disease BEFREE Inhibition of PLK1 by RNAi significantly decreased medulloblastoma cell proliferation and clonogenic potential and increased cell apoptosis. 22390279 2012
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		0.070 Biomarker disease BEFREE PLK1 (polo-like kinase 1) was identified as a kinase involved in proliferation in medulloblastoma cell lines. 21652733 2011