Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100379198
Gene Symbol: ECT
ECT 		0.020 Biomarker disease BEFREE This study considered dexamethasone suppression test (DST) results, Winokur 's familial subtyping, and the presence or absence of melancholia according to DSM-III criteria as potential predictors of response to ECT. 6731634 1984
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.300 Biomarker disease CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106 2006
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		0.300 Biomarker disease CTD_human Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder. 16861106 2006
Entrez Id: 2495
Gene Symbol: FTH1
FTH1 		0.300 Biomarker disease CTD_human The relationship between depression and serum ferritin level. 17063146 2007
Entrez Id: 2512
Gene Symbol: FTL
FTL 		0.300 Biomarker disease CTD_human The relationship between depression and serum ferritin level. 17063146 2007
Entrez Id: 51738
Gene Symbol: GHRL
GHRL 		0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 2739
Gene Symbol: GLO1
GLO1 		0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 2782
Gene Symbol: GNB1
GNB1 		0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 2931
Gene Symbol: GSK3A
GSK3A 		0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.300 Biomarker disease CTD_human A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. 20534517 2010
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.010 GeneticVariation disease BEFREE In order to further delineate the impact of 5-HT1A gene variation on pharmacoresponse in depression over 6 weeks of antidepressant treatment, the influence of the 5-HT1A-1019C/G (rs6295) polymorphism was investigated in 340 Caucasian patients with a Major Depressive Episode (DSM-IV) with particular attention to the subtype of depression (major depression and melancholic depression). 18387740 2008
Entrez Id: 3363
Gene Symbol: HTR7
HTR7 		0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2 		0.300 Biomarker disease CTD_human Factors influencing long-term changes in mental health after interferon-alpha treatment of chronic hepatitis C. 19691667 2009
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2 		0.300 Biomarker disease CTD_human Emotional distress during interferon-alpha-2B and ribavirin treatment of chronic hepatitis C. 12297606 2002
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2 		0.300 Biomarker disease CTD_human A randomized trial of paroxetine to prevent interferon-alpha-induced depression in patients with hepatitis C. 17292481 2007
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2 		0.300 Biomarker disease CTD_human Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis C. 17451562 2007
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		0.010 AlteredExpression disease BEFREE Melancholic depression is associated with increased sIL-6R but lowered IL-1α levels. 29103192 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.010 AlteredExpression disease BEFREE Patients with MDD with melancholic features showed higher IL-1β levels than those without melancholia. 31693974 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2 		0.300 Biomarker disease CTD_human 5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques. 21871532 2011
Entrez Id: 4282
Gene Symbol: MIF
MIF 		0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker disease CTD_human Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. 17074966 2007
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		0.300 Biomarker disease CTD_human Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis. 17854383 2007
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Therapeutic disease CTD_human Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: region specific adaptation after fluoxetine treatment. 9729278 1998