|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
The HOM-MEL-40 antigen which is encoded by the SSX-2 gene was originally detected as a tumor antigen recognized by autologous IgG antibodies in a melanoma patient.
|
9639388 |
1998 |
|
LINC01194
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In summary, MAP kinase inhibitors (MAPKi) strongly alter the tumor antigen expression profile over time, favoring evolution of melanoma variants cross-resistant to both T cells and MAPKi.
|
30221038 |
2018 |
|
LINC01194
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
To investigate this, we determined the specificity of T cells from melanoma patients treated with DCs loaded with mRNA encoding a full-length tumor antigen fused to a signal peptide and an HLA class II sorting signal, allowing presentation in HLA class I and II.
|
22371843 |
2012 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1.
|
7561675 |
1995 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
The tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4) appears to be a useful biomarker to identify melanoma cells and an attractive target to apply antibody-based immunotherapy for the treatment of melanoma.
|
24258997 |
2014 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
The MART-1/Melan-A human melanoma tumor antigen can be recognized by T lymphocytes and appears to be involved in tumor regression.
|
9218710 |
1997 |
|
LINC01194
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Tumor antigen expression in melanoma varies according to antigen and stage.
|
16467087 |
2006 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro.
|
16645618 |
2006 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
The properties of the TAG antigens indicate that they are excellent vaccine candidates for the treatment of melanoma and perhaps other cancers.
|
14871852 |
2004 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
Discrepancy Between Tumor Antigen Distribution and Radiolabeled Antibody Binding in a Nude Mouse Xenograft Model of Human Melanoma.
|
28380302 |
2017 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here, we determined that TIGIT is upregulated on tumor antigen-specific (TA-specific) CD8⁺ T cells and CD8⁺ tumor-infiltrating lymphocytes (TILs) from patients with melanoma, and these TIGIT-expressing CD8⁺ T cells often coexpress the inhibitory receptor PD-1.
|
25866972 |
2015 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
Associated with tumor regression was also loss of the melanoma common tumor antigen Melan A/ MART-1 in the multiple primary melanoma patients as compared to the single primary ones (P=0.0041).
|
16248806 |
2005 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes.
|
7836932 |
1995 |
|
LINC01194
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
TriMix DCs coelectroporated with whole tumor-antigen mRNA stimulate antigen-specific T cells in vitro and induce antigen-specific T-cell responses in melanoma patients through vaccination.
|
19417017 |
2009 |
|
LINC01194
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, we discuss the roles of emerging molecular players that are involved in melanoma pathogenesis, including the functional role of the melanoma tumor antigen, p97/MFI2 (melanotransferrin).
|
26844774 |
2016 |
|
LINC01194
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo.
|
17449903 |
2007 |