| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | Taken together, our results demonstrated that miR-10b was an important epigenetic modifier, promoting melanoma progression through regulating ITCH/Wnt/β-catenin pathway. | 31129246 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Taken together our results suggest that miR-10b is an important mediator of oncogenic B-RafV600E activity in melanoma. | 30995246 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Collectively, our study suggests that serum miR-10b level is upregulated in melanoma and associated with poor prognosis. | 28900486 | 2017 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | In the combined discovery and validation cohorts (n=79), miR-10b expression showed a 3.7-fold increase in expression between cases and controls (P=0.005) and showed a trend of increasing expression between primary melanomas and their matched metastases (P<0.001). | 26743475 | 2016 | ||||
|
0.070 | Biomarker | disease | BEFREE | Evaluation of the expressions pattern of miR-10b, 21, 200c, 373 and 520c to find the correlation between epithelial-to-mesenchymal transition and melanoma stem cell potential in isolated cancer stem cells. | 26208390 | 2015 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | It was found that vestibular schwannomas ranked first among the reported cancer types with up-regulated microRNA-10b expression; melanoma ranked first among the reported cancer types with down-regulated microRNA-10b expression; while breast cancer and hepatocellular cancer presented inconsistent microRNA-10b regulation. | 25510966 | 2014 | ||||
|
0.070 | Biomarker | disease | BEFREE | Primary melanoma in patients greater than 60 years old was characterized by the increased expression of miRs regulating TLR-MyD88-NF-kappaB pathway (hsa-miR-199a), RAS/RAB22A pathway (hsa-miR-204); growth differentiation and migration (hsa-miR337), epithelial mesenchymal transition (EMT) (let-7b, hsa-miR-10b/10b*), invasion and metastasis (hsa-miR-10b/10b*), hsa-miR-30a/e*, hsa-miR-29c*; cellular matrix components (hsa-miR-29c*); invasion-cytokinesis (hsa-miR-99b*) compared to melanoma of younger patients. | 20302635 | 2010 |