Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 Biomarker disease BEFREE In this study, we investigated the role of methylation in reduced XPC in melanoma. 29373959 2018
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 AlteredExpression disease BEFREE Expression of GGR components XPC, DDB1 and DDB2 was significantly lower in melanoma after UVB. 27487145 2016
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro), and GSTP1 (Ile105Val) polymorphisms in prognosis of cutaneous melanoma. 26427666 2016
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE In addition, there was some evidence of publication bias in the meta-analysis, and meta-analyses of the studies with large sample size did not find the obvious association between XPC Lys939Gln polymorphism and cutaneous melanoma risk in Caucasians. 24277375 2014
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 Biomarker disease BEFREE Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC. 23650282 2013
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE Assessment of the XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro) and GSTP1 (Ile105Val) polymorphisms in the risk of cutaneous melanoma. 23568549 2013
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 Biomarker disease BEFREE Severe XPA and XPC cause innumerable carcinomas and melanomas in light-exposed eyes and skin, and enhanced risk of visceral cancers. 23622385 2013
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE Melanoma risk was higher in individuals carrying the complete XPC haplotype than each individual polymorphism (OR 3.64; 95% CI 1.77-7.48). 21733660 2011
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE ORs for XPD and XPC genotypes were stronger for melanoma diagnosed at an early age, but tests for interaction were not statistically significant. 16258177 2006
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE We investigated the role of three polymorphic alleles of the DNA repair gene XPC in a hospital-based case-control study of 294 Caucasian patients from Germany who had cutaneous melanoma and 375 healthy cancer-free sex-matched Caucasian control subjects from the same area. 15731165 2005
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 GeneticVariation disease BEFREE We investigated the role of three variant alleles of the DNA repair gene XPC and one variant allele of the XPG gene in a hospital-based case-control study of 294 Caucasian patients from Germany with malignant melanoma and 375 healthy control individuals from the same area matched by sex. 15494739 2005
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 CausalMutation disease CGI
Entrez Id: 7508
Gene Symbol: XPC
XPC
0.500 Biomarker disease HPO