Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 Biomarker group BEFREE Paraoxonase 1 (PON1) is an important antiatherogenic and antioxidant enzyme in the circulation that has been associated with adverse health outcomes particularly cardiovascular disease (CVD) and other metabolic disorders. 31351988 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 GeneticVariation group BEFREE L55M polymorphism, like exposure to tobacco smoke and overweight, disorders PON1 status and lipid profile parameters; therefore, it could be a crucial risk factor for the development of many metabolic disorders. 30618305 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 Biomarker group BEFREE These results indicate that PON-1 is paradoxically maintained and may even be increased in NAFLD despite inverse associations with metabolic disorders and low HDL cholesterol. 30455362 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 AlteredExpression group BEFREE The aim of this review is to elucidate the physiological role of PON1, as well as the impact of altered PON1 levels in metabolic disorders. 31430977 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 Biomarker group BEFREE SR-BI deficiency leading to dysfunctional HDL is closely related to alteration of HDL protein, suggesting that identification of apoAI, PON1, SAA, apoAIV, and A1AT may serve as the valuable protein markers for diagnosis and therapeutics of dysfunctional HDL-related metabolic diseases. 29879989 2018
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 Biomarker group CTD_human Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk-an exploratory study. 28396702 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.360 GeneticVariation group BEFREE None of the variants of the Leu55Met PON1 polymorphism was associated with more frequent occurrence of PCOS or metabolic disorders, including insulin resistance. 20334584 2010