Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE Injection site reactions (ISRs) and influenza-like illness are the most common adverse effects of interferon beta therapies and can present a burden for MS patients leading to non-adherence and discontinuation of therapy. 31202258 2019
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE Interferon beta (IFN-β) benefits patients with MS and reduces symptoms of the RR-MS. MxA is induced by type I interferon and predicts IFN-β response in MS patients. 31421628 2019
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE IFNβ-1a injections will damage qi and cause blood stasis in MS patients, thereby causing various side effects and weakening the body's immune system. 29458918 2018
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 AlteredExpression disease BEFREE Early MRI results and odds of attaining 'no evidence of disease activity' status in MS patients treated with interferon β-1a in the EVIDENCE study. 28716230 2017
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE The humoral immune response to IFN-β observed in MS patients as a result of IFN-β therapy is a multifactorial process that is influenced by ADA titers, affinity maturation, and IgG subclass switching. 28418769 2017
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE This study investigated the influence of HLA class-I and -II genes in the response to IFN-β in relapsing-remitting multiple sclerosis (MS) patients. 27020477 2016
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE Our findings confirmed the lack of association between HLA-DRB1 and clinical response to IFNβ among MS patients as previous studies had done. 25824849 2015
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 AlteredExpression disease BEFREE In this study, IFNβ-1b-treated MS patient gene expression profiles and biological knowledgebases were integrated to study IFNβ's pleiotropic mechanisms of action. 22711062 2013
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 AlteredExpression disease BEFREE R(+)WIN55,212-2 also induces IFN-β expression in MS patient peripheral blood mononuclear cells, whereas down-regulating inflammatory signaling in these cells. 21245146 2011
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 GeneticVariation disease BEFREE An IFNG polymorphism is associated with interferon-beta response in Spanish MS patients. 16430971 2006
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.100 Biomarker disease BEFREE Persistent neutralizing antibodies abolish the interferon beta bioavailability in MS patients. 12601105 2003
Entrez Id: 2200
Gene Symbol: FBN1
FBN1 		0.100 Biomarker disease HPO
Entrez Id: 55784
Gene Symbol: MCTP2
MCTP2 		0.100 Biomarker disease HPO
Entrez Id: 64131
Gene Symbol: XYLT1
XYLT1 		0.100 Biomarker disease HPO
Entrez Id: 5337
Gene Symbol: PLD1
PLD1 		0.100 Biomarker disease HPO
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2 		0.100 Biomarker disease HPO
Entrez Id: 368
Gene Symbol: ABCC6
ABCC6 		0.100 Biomarker disease HPO
Entrez Id: 9469
Gene Symbol: CHST3
CHST3 		0.100 Biomarker disease HPO
Entrez Id: 2697
Gene Symbol: GJA1
GJA1 		0.100 Biomarker disease HPO
Entrez Id: 1482
Gene Symbol: NKX2-5
NKX2-5 		0.100 Biomarker disease HPO
Entrez Id: 9719
Gene Symbol: ADAMTSL2
ADAMTSL2 		0.100 Biomarker disease HPO
Entrez Id: 7707
Gene Symbol: ZNF148
ZNF148 		0.100 Biomarker disease HPO
Entrez Id: 64132
Gene Symbol: XYLT2
XYLT2 		0.100 Biomarker disease HPO
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		0.100 Biomarker disease HPO
Entrez Id: 2629
Gene Symbol: GBA
GBA 		0.100 Biomarker disease HPO