Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 Biomarker disease BEFREE We show that PTC-209 reduces the viability of MM cells via induction of apoptosis and reveal that the anti-MM actions of PTC-209 are mediated by on-target effects i.e. downregulation of BMI-1 protein and the associated repressive histone mark H2AK119ub, leaving other PRC1 subunits such as CBX-7 and the catalytic subunit RING1B unaffected. 29262596 2017
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 GeneticVariation disease GWASCAT Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. 27363682 2016
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 GeneticVariation disease BEFREE SNPs correlated with the index signal in 22q13.1 cluster around the promoter and enhancer regions of CBX7 CONCLUSIONS: We found that reported multiple myeloma susceptibility regions contain risk variants important across populations, supporting the use of multiple racial/ethnic groups with different underlying genetic architecture to enhance the localization and identification of putatively functional alleles. 27587788 2016
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 GeneticVariation disease GWASCAT Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. 23955597 2013
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 Biomarker disease CTD_human Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. 23955597 2013
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 GeneticVariation disease GWASCAT The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. 23502783 2013
Entrez Id: 23492
Gene Symbol: CBX7
CBX7
0.420 GeneticVariation disease GWASDB Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. 23955597 2013