Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Diffuse large B-cell lymphoma (DLBCL) and multiple myeloma (MM) cells infected by EBV display drug resistance-related proteins (MDR1, MRP1 and MRP2) and stem cell markers (OCT4 and SOX2). | 28339079 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | We have described a new method for the determination of P-gp and MRP activity suitable for use in clinical studies and have optimized this method to include a gating strategy, allowing routine use on PCM bone marrow aspirate samples. | 22434582 | 2012 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | CD40 stimulation induces vincristine resistance via AKT activation and MRP1 expression in a human multiple myeloma cell line. | 22445357 | 2012 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The low activity of MDR- 1 and MRP-1 in MM need further clarification, indicating the involvement of different transport in the resistance mechanism. | 15739024 | 2005 | ||||
|
0.080 | Biomarker | disease | BEFREE | MDR1, MRP1 and LRP have been identified as important adverse prognostic factors in AML, T-ALL and MM. | 10809991 | 2000 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Acute myelocytic leukemia often exhibited low but occasionally high MRP expression levels, while in the other acute and chronic leukaemias, lymphomas, and multiple myeloma, predominantly low, basal levels of MRP were found. | 8833393 | 1996 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | All myeloma patients (12 of 12) had detectable MRP mRNA expression at levels comparable to normal peripheral blood and bone marrow cells. | 8062263 | 1994 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In contrast, low MRP mRNA expression levels were detected in hairy cell leukaemia (n = 7), non-Hodgkin's lymphoma (n = 13) and multiple myeloma (n = 18). | 7803281 | 1994 |