Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.030 Biomarker disease BEFREE A functional connection between talin/kindlin-3 and Rac1 was found to be required for MM cell attachment mediated by α4β1. 26658839 2016
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.030 Biomarker disease BEFREE CXCL12 and S1P activated the DOCK2-Rac1 pathway, which was required for stimulation of myeloma cell adhesion involving α4β1. 22711564 2013
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.030 Biomarker disease BEFREE Mechanistically, ITGB7 knockdown inhibited focal adhesion kinase (FAK) and Src phosphorylation, Rac1 activation, and SUMOylation, reduced VEGF production in MM-BM stem cell cocultures and attenuated p65-NF-κB activity. 21474670 2011