Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 AlteredExpression disease BEFREE The expression levels of IGF-1 and ERK in MS patients with CRC were higher while expression levels of GLUT4 were lower compared to MS patients without CRC (P< 0.01). 29504525 2018
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 Biomarker disease BEFREE Polymorphisms in the genes encoding interleukin-23 receptor (IL23R) and the p40 subunit of IL-12/23 (IL12B) have been implicated in multiple sclerosis (MS) risk. 26000455 2016
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 GeneticVariation disease GWASCAT Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 GeneticVariation disease GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 Biomarker disease BEFREE We also show that p38 MAPK activation is required for the development and progression of both chronic and relapsing-remitting forms of experimental allergic encephalomyelitis (EAE), the principal autoimmune model of multiple sclerosis. 21791428 2011
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 GeneticVariation disease GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 GeneticVariation disease BEFREE Interleukin (IL)-12 is thought to play an important role in the development of atherosclerosis and recently, polymorphism of the 3'-untranslated region of the IL-12 p40 gene (A1188C) was reported to be associated with diabetes and multiple sclerosis. 15988104 2005
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 AlteredExpression disease BEFREE Our findings are of value for the interpretation of previous findings of p41 expression in brains of MS patients and may allow a more detailed analysis of the role of HHV-6 variants in other disorders. 11283070 2001
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.160 Biomarker disease BEFREE No decrease in the production of the IL-12 p40 was seen in MS patients on IFN-beta therapy. 10516776 1999