Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.160 | AlteredExpression | disease | BEFREE | The expression levels of IGF-1 and ERK in MS patients with CRC were higher while expression levels of GLUT4 were lower compared to MS patients without CRC (P< 0.01). | 29504525 | 2018 | ||||
|
0.160 | Biomarker | disease | BEFREE | Polymorphisms in the genes encoding interleukin-23 receptor (IL23R) and the p40 subunit of IL-12/23 (IL12B) have been implicated in multiple sclerosis (MS) risk. | 26000455 | 2016 | ||||
|
0.160 | GeneticVariation | disease | GWASCAT | Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. | 24076602 | 2013 | ||||
|
0.160 | GeneticVariation | disease | GWASDB | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. | 21833088 | 2011 | ||||
|
0.160 | Biomarker | disease | BEFREE | We also show that p38 MAPK activation is required for the development and progression of both chronic and relapsing-remitting forms of experimental allergic encephalomyelitis (EAE), the principal autoimmune model of multiple sclerosis. | 21791428 | 2011 | ||||
|
0.160 | GeneticVariation | disease | GWASCAT | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. | 21833088 | 2011 | ||||
|
0.160 | GeneticVariation | disease | BEFREE | Interleukin (IL)-12 is thought to play an important role in the development of atherosclerosis and recently, polymorphism of the 3'-untranslated region of the IL-12 p40 gene (A1188C) was reported to be associated with diabetes and multiple sclerosis. | 15988104 | 2005 | ||||
|
0.160 | AlteredExpression | disease | BEFREE | Our findings are of value for the interpretation of previous findings of p41 expression in brains of MS patients and may allow a more detailed analysis of the role of HHV-6 variants in other disorders. | 11283070 | 2001 | ||||
|
0.160 | Biomarker | disease | BEFREE | No decrease in the production of the IL-12 p40 was seen in MS patients on IFN-beta therapy. | 10516776 | 1999 |