| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.060 | Biomarker | group | BEFREE | Detection of <i>Dialister micraerophilus</i> (p=0.01), <i>Eggerthella</i> sp type 1 (p=0.05) or <i>Mycoplasma hominis</i> (p=0.03) was associated with higher TNFα concentrations, and detection of <i>D. micraerophilus</i> (p<0.01)<i>, Eggerthella</i> sp type 1 (p=0.04)<i>, M. hominis</i> (p=0.02) or <i>Parvimonas</i> sp type 2 (p=0.05) was associated with significantly higher IL-1β concentrations.Seven bacterial taxa (<i>D. micraerophilus</i>, <i>Eggerthella</i> sp type 1, <i>Gemella asaccharolytica, Sneathia</i> sp, <i>Megasphaera</i> sp, <i>M. hominis</i> and <i>Parvimonas</i> sp type 2) were found to be highly correlated by principal component analysis (eigenvalue 5.24, explaining 74.92% of variability). | 31197065 | 2020 | ||||
|
0.060 | Biomarker | group | BEFREE | Serum Tumor Necrosis Factor-<i>α</i> and Interferon-<i>γ</i> Levels in Pediatric <i>Mycoplasma pneumoniae</i> Pneumonia: A Systematic Review and Meta-Analysis. | 30275916 | 2018 | ||||
|
0.060 | Biomarker | group | BEFREE | These mediators include classical pro-inflammatory cytokines such as TGF-β, TNF-α, interferons, or IL-1β that are released upon bacterial challenge with <i>Streptococcus pneumoniae, Klebsiella pneumoniae</i>, or <i>Mycoplasma pneumoniae</i> as well as in viral infection with influenza A virus, pathogenic coronaviruses, or respiratory syncytial virus. | 28458673 | 2017 | ||||
|
0.060 | GeneticVariation | group | BEFREE | Study of polymorphic variants of the TNF gene in pregnant women with mycoplasma infection in the Kazakh population. | 27759455 | 2016 | ||||
|
0.060 | AlteredExpression | group | BEFREE | We describe a case of rhabdomyolysis in a patient infected with antimicrobial drug-resistant Mycoplasma pneumoniae The patient's acute-phase serum levels of interleukin-18 and tumor necrosis factor-α were high, which suggests a pathogenic role for M. pneumoniae. | 22515975 | 2012 | ||||
|
0.060 | Biomarker | group | BEFREE | Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice. | 22502799 | 2012 |