Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group BEFREE BCR-FGFR1, CNTRL-FGFR1, CUX1-FGFR1, FGFR1OP-FGFR1, MYO18A-FGFR1 and ZMYM2-FGFR1 fusions in myeloproliferative neoplasms are non-receptor-type FGFR kinases, whereas FGFR1-TACC1, FGFR2-AFF3, FGFR2-BICC1, FGFR2-PPHLN1, FGFR3-BAIAP2L1 and FGFR3-TACC3 fusions in solid tumors are transmembrane-type FGFRs with C-terminal alterations. 27245147 2016
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group CTD_human Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome. 22875613 2013
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 GeneticVariation group BEFREE Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease. 21527531 2011
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group BEFREE Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS. 19658100 2009
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 GeneticVariation group BEFREE Combined translocation with ZNF198-FGFR1 gene fusion and deletion of potential tumor suppressors in a myeloproliferative disorder. 17321332 2007
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 AlteredExpression group BEFREE Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease. 16410451 2006
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group BEFREE ZNF198, a zinc finger protein rearranged in myeloproliferative disease, localizes to the PML nuclear bodies and interacts with SUMO-1 and PML. 17027752 2006
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 GeneticVariation group BEFREE Mass spectroscopy identifies the splicing-associated proteins, PSF, hnRNP H3, hnRNP A2/B1, and TLS/FUS as interacting partners of the ZNF198 protein associated with rearrangement in myeloproliferative disease. 15975576 2005
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group BEFREE The t(8;13) translocation, found in a rare and aggressive type of stem cell myeloproliferative disorder, leads to the generation of a fusion protein between the N-terminal gene product of fused in myeloproliferative disorders (FIM)/ZNF198 and the fibroblast growth factor receptor 1 (FGFR1) kinase domain. 14672707 2004
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group BEFREE ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins. 12776193 2003
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 GeneticVariation group BEFREE The t(8;13) translocation found in a rare type of stem cell myeloproliferative disorder generates a constitutively activated tyrosine kinase containing N-terminal sequence encoded by the FIM gene linked to the FGFR1 kinase domain. 10480903 1999
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.400 Biomarker group BEFREE By analogy with these, we propose that the RAMP-FGFR1 fusion product will contribute to progression of this myeloproliferative disorder by constitutive activation of tyrosine kinase function. 9499416 1998