Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3060
Gene Symbol: HCRT
HCRT 		0.700 Biomarker disease HPO
Entrez Id: 4340
Gene Symbol: MOG
MOG 		0.630 Biomarker disease CTD_human
Entrez Id: 4340
Gene Symbol: MOG
MOG 		0.630 Biomarker disease HPO
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		0.150 Biomarker disease HPO
Entrez Id: 28954
Gene Symbol: REM1
REM1 		0.100 Biomarker disease BEFREE One sister suffered from all the symptoms of narcolepsy and her sleep recording showed the typical sleep onset REM periods of the disease. 227489 1979
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1 		0.200 Biomarker disease BEFREE None of the patients was DQB1-0602 or DQA1-0102 positive, thus proving that, in caucasians, DQB1-0602 and DQA1-0102 (DQw1) are not prerequisites for the diagnosis of narcolepsy. 1455124 1992
Entrez Id: 28954
Gene Symbol: REM1
REM1 		0.100 Biomarker disease BEFREE HLA DR2 in narcolepsy with sleep-onset REM periods but not cataplexy. 1751625 1991
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.040 Biomarker disease BEFREE Narcolepsy is a sleep disorder completely associated with HLA-DR2,Dw2. 2494138 1989
Entrez Id: 7200
Gene Symbol: TRH
TRH 		0.300 Biomarker disease CTD_human Inhibition of the binding and the behavioral effects of thyrotropin-releasing hormone (TRH) by the triazolobenzodiazepines. 2845442 1988
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.040 GeneticVariation disease BEFREE These findings indicate that narcolepsy is associated worldwide with the HLA-DR2,Dw2 haplotype. 2896649 1988
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.040 Biomarker disease BEFREE It was concluded that HLA-DR2 is a prerequisite for the development of narcolepsy and that the diagnosis of narcolepsy can be excluded if HLA-DR2 or HLA-Dw2 is negative. 3010426 1986
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.040 GeneticVariation disease BEFREE Narcolepsy has a 98% association with the DR2-Dw2/DQw1 haplotype. 3259543 1988
Entrez Id: 5905
Gene Symbol: RANGAP1
RANGAP1 		0.010 Biomarker disease BEFREE These data show that there is no significant segregation distortion of the DR2/DQw1 haplotype in Japanese patients with narcolepsy. 3263961 1988
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.700 Biomarker disease BEFREE In Black Americans, however, DRB1*1501 (DR2) was a poor marker for narcolepsy. 7701202 1994
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1 		0.200 Biomarker disease BEFREE These results demonstrate that DQB1*0602/DQA1*0102 is the best marker for narcolepsy across all ethnic groups. 7701202 1994
Entrez Id: 129831
Gene Symbol: RBM45
RBM45 		0.100 Biomarker disease BEFREE In Black Americans, however, DRB1*1501 (DR2) was a poor marker for narcolepsy. 7701202 1994
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.700 GeneticVariation disease BEFREE A deletion in the second exon of an HLA-DRB1 allele found in a DR2-negative narcolepsy patient. 7980729 1993
Entrez Id: 28954
Gene Symbol: REM1
REM1 		0.100 GeneticVariation disease BEFREE Narcolepsy is a genetically determined disorder of sleep characterized by excessive daytime sleepiness and abnormal manifestations of REM sleep that affects both humans and animals. 8095066 1993
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1 		0.200 Biomarker disease BEFREE We conclude that HLA DQA1*0102 and DQB1*0602 are the most likely primary candidate susceptibility genes for narcolepsy in the HLA class II region. 9151385 1997
Entrez Id: 3118
Gene Symbol: HLA-DQA2
HLA-DQA2 		0.110 Biomarker disease BEFREE We conclude that HLA DQA1*0102 and DQB1*0602 are the most likely primary candidate susceptibility genes for narcolepsy in the HLA class II region. 9151385 1997
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.800 Biomarker disease BEFREE Human narcolepsy is tightly associated with HLA-DQB1*0602; canine narcolepsy is linked with a DNA segment with high homology with the human immunoglobulin mu-switch segment, and the onset of canine narcolepsy is associated with increased microglial expression of major histocompatibility complex DQ and DR molecules. 9363189 1996
Entrez Id: 28954
Gene Symbol: REM1
REM1 		0.100 Biomarker disease BEFREE HLA typing was incompatible with narcolepsy or REM sleep behavioural disorder. 9436739 1998
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.800 GeneticVariation disease BEFREE These results could be explained by increased disease heterogeneity in the noncataplexy group or by a direct effect of the HLA DQB1*0602 genotype on the clinical expression of narcolepsy. 9456467 1997
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.700 Biomarker disease BEFREE DQB1*0602 was found to be a more sensitive marker for narcolepsy than DRB1*15 across all ethnic groups. 9456467 1997
Entrez Id: 129831
Gene Symbol: RBM45
RBM45 		0.100 Biomarker disease BEFREE DQB1*0602 was found to be a more sensitive marker for narcolepsy than DRB1*15 across all ethnic groups. 9456467 1997