Gene: IL21 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 59067
Gene Symbol: IL21
IL21 		0.040 AlteredExpression disease BEFREE Increased TSLP, IL-33, IL-25, IL-19, IL 21 and amphiregulin (AREG) levels in chronic rhinosinusitis with nasal polyp. 30888496 2019
Entrez Id: 59067
Gene Symbol: IL21
IL21 		0.040 AlteredExpression disease BEFREE Furthermore, SEB was able to increase IL-21 mRNA expression significantly (p < 0.01) in nasal polyps. 29131072 2017
Entrez Id: 59067
Gene Symbol: IL21
IL21 		0.040 Biomarker disease BEFREE CRSwNP patients had significantly more tissue IL-17A (9.53 ± 2.71 vs. 1.11 ± 0.43 vs. 0.77 ± 0.07), IL-17F (4.96 ± 1.48 vs. 0.88 ± 0.31 vs. 0.56 ± 0.04), IL-21 (5.55 ± 2.01 vs. 1.60 ± 0.71 vs. 1.53 ± 0.55) and IL-22 (4.73 ± 1.58 vs. 0.70 ± 0.28 vs. 0.88 ± 0.26) producing Th17 cells compared to CRSsNP and control mucosa per mg of tissue, respectively. 29311948 2017
Entrez Id: 59067
Gene Symbol: IL21
IL21 		0.040 Biomarker disease BEFREE These findings indicated that IL-12 positively enhanced the generation of IL-21(+)IFN-γ(+)CD4(+) T cells having the features of both Tfh and Th1 cells in NP tissues. 26239551 2015