Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.060 GeneticVariation phenotype BEFREE Effect of the allelic variants of ABCB1, CYP2D6 and HTR3B on response of ramosetron to prevent chemotherapy-induced nausea and vomiting in Korean cancer patients. 27488933 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.060 GeneticVariation phenotype BEFREE Based on our hypothesis that this clinical resistance to ondansetron is associated with ABCB1 genetic polymorphisms, we investigated whether ABCB1 gene variations affect the efficacy of ondansetron in chemotherapy-induced nausea and vomiting. 25012726 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.060 GeneticVariation phenotype BEFREE Within the first 24 hours of chemotherapy, the complete control rate of nausea and vomiting was higher in subjects with the ABCB1 TT genotype (n = 49) as compared with those with the CC (n = 60) or CT (n = 107) genotype (P = .044). 16338277 2005
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.060 GeneticVariation phenotype BEFREE Comparison of Ramosetron and Palonosetron for Preventing Nausea and Vomiting after Spinal Surgery: Association With ABCB1 Polymorphisms. 27564555 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.060 GeneticVariation phenotype BEFREE Carriers of the CTG haplotype of the ABCB1 gene experienced Grade 3 and 4 chemotherapy-induced nausea and vomiting more often than other haplotypes in the delayed phase (P< 0.05). 21840870 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.060 Biomarker phenotype BEFREE In stratified regression models including demographical and disease-related factors as covariates, 96 single nucleotide polymorphisms (SNPs) in 16 candidate genes related to opioid- or nausea/vomiting signalling pathways (ABCB1, OPRM1, OPRK1, ARRB2, STAT6, COMT, CHRM3, CHRM5, HRH1, DRD2, DRD3, TACR1, HTR3A, HTR3B, HTR3C, CNR1) were analysed for association with nausea and vomiting. 21570824 2011
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
0.010 AlteredExpression phenotype BEFREE In contrast, activation of ABCC1 using thiethylperazine (a drug approved by the FDA to relieve nausea and vomiting) markedly reduced Aβ load in a mouse model of AD expressing ABCC1 but not in such mice lacking ABCC1. 21881209 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.010 Biomarker phenotype BEFREE The most common reaction for opiates was nausea/vomiting (17.9%, n = 211 864), cough/coughing for ACE inhibitors (41.0%, n = 270 537) and muscle pain/myalgia for statins (34.1%, n = 186 565). 27862587 2017
Entrez Id: 72
Gene Symbol: ACTG2
ACTG2
0.100 Biomarker phenotype HPO
Entrez Id: 213
Gene Symbol: ALB
ALB
0.010 AlteredExpression phenotype BEFREE Time to get out of bed, first bowel movement time and the average time of hospitalisation in group A was lower than group D (p less than 0.05), postoperative leukocyte level as well as the occurrence rate of nausea and vomiting, ankylenteron and pelvic adhesion was decreased in group A compared to group D (p less than 0.05), but the postoperative albumin and total protein level was higher than group D (p less than 0.05). 29254317 2018
Entrez Id: 283
Gene Symbol: ANG
ANG
0.100 Biomarker phenotype HPO
Entrez Id: 311
Gene Symbol: ANXA11
ANXA11
0.100 Biomarker phenotype HPO
Entrez Id: 359
Gene Symbol: AQP2
AQP2
0.100 Biomarker phenotype HPO
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
0.100 Biomarker phenotype HPO
Entrez Id: 546
Gene Symbol: ATRX
ATRX
0.100 Biomarker phenotype HPO
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
0.100 Biomarker phenotype HPO
Entrez Id: 554
Gene Symbol: AVPR2
AVPR2
0.100 Biomarker phenotype HPO
Entrez Id: 27087
Gene Symbol: B3GAT1
B3GAT1
0.010 Biomarker phenotype BEFREE Current therapy for chemotherapy-induced nausea and vomiting includes the use of both 5-HT3 and NK1 receptor antagonists. 24969614 2014
Entrez Id: 9531
Gene Symbol: BAG3
BAG3
0.010 Biomarker phenotype BEFREE Given the results of this study, it seems that general anesthesia with propofol and remifentanil with L-BIS causes less need for additional analgesic drug and less nausea and vomiting compared to anesthesia with H-BIS. 29026334 2017
Entrez Id: 9031
Gene Symbol: BAZ1B
BAZ1B
0.100 Biomarker phenotype HPO
Entrez Id: 8915
Gene Symbol: BCL10
BCL10
0.100 Biomarker phenotype HPO
Entrez Id: 330
Gene Symbol: BIRC3
BIRC3
0.100 Biomarker phenotype HPO
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A
0.100 Biomarker phenotype HPO
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.100 Biomarker phenotype HPO
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.100 Biomarker phenotype HPO