Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity. 20209495 2010
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 and nm23-H2 are putative metastasis suppressor genes that encode nucleoside diphosphate kinase (NDPK) A and B. NDPKs form oligomers distributed between soluble and particulate fractions of cells and therefore may exert their effects as either soluble or bound proteins. 11058869 2000
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23 gene family has been associated with metastasis suppression and differentiation. 11464913 2001
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway. 12105213 2002
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 may therefore play an important role in suppressing the early steps of metastasis in sporadic cases of colorectal carcinomas. 12684753 2004
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 encodes nucleoside diphosphate kinase A and acts as a suppressor of metastasis in certain human tumors. 16814409 2006
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE NM23, the first metastasis suppressor gene to be identified, has been widely studied in human cancers. 16944304 2007
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE NM23 is one of the human metastasis suppressor genes. 17885583 2007
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 AlteredExpression phenotype BEFREE Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2. 18089805 2008
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 was discovered as the first metastasis suppressor gene about 20 years ago. 19412732 2009
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 is a well-known tumor metastasis suppressor, which functions as a nucleoside-diphosphate kinase converting nucleoside diphosphates to nucleoside triphosphates with an expense of ATP. 20448457 2011
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE nm23, a tumor metastasis suppressor gene, has been linked to protection against tumorigenesis and tumor metastasis. 22683585 2012
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma. 22699362 2013
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE NME1 is a wide-spectrum tumor metastasis suppressor gene that plays an important role in suppressing the invasion and metastasis of tumor cells. 23856325 2014
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-h1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis. 23940300 2013
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23-H1 is a metastasis suppressor gene whose overexpression is associated with both reduced cell motility in various cancers and increased metastatic potential in neuroblastomas, osteosarcomas, and hematological malignances. 25138575 2015
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23 is a metastasis suppressor gene whose downregulation triggers metastatic progression. 25321081 2015
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE nm23 has properties of a metastasis suppressor gene and also has been implicated in the control of response to transforming growth factor beta 1 (TGF beta 1) by studies in melanoma cells. 7819128 1995
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 AlteredExpression phenotype BEFREE NM23 expression in metastasis of malignant melanoma is a predictive prognostic parameter correlated with survival. 7981081 1995
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 GeneticVariation phenotype BEFREE Nm23 is a putative metastasis suppressor gene and alterations in this gene have been reported in colorectal carcinomas suggestive of a role for nm23 in the dissemination of these tumours. 8195929 1994
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23 is a gene associated with low tumor metastatic potential and has been proposed to be a metastasis suppressor gene. 8199988 1994
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE Nm23 and breast cancer metastasis. 8347849 1993
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE nm23 has been recognized as a potential suppressor gene of metastasis. 9570214 1998
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 AlteredExpression phenotype BEFREE nm23 Protein expression in larynx cancer and the relationship with metastasis. 9616278 1998
Entrez Id: 4830
Gene Symbol: NME1
NME1
0.400 Biomarker phenotype BEFREE A human gene, nm23-H1, has been known as a metastasis suppressor in many tumor cells. 10072163 1999