Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | AlteredExpression | phenotype | BEFREE | Taken together, our results suggest that PELP1 regulates tumor metastasis by controlling the expression and functions of the tumor metastasis suppressors miR-200a and miR-141. | 23975430 | 2014 | ||||
|
0.100 | Biomarker | phenotype | BEFREE | miR-141 serves as a potential biomarker for discriminating ccRCC from normal tissues and a crucial suppressor of ccRCC cell proliferation and metastasis by modulating the EphA2/p-FAK/p-AKT/MMPs signaling cascade. | 24647573 | 2014 | ||||
|
0.100 | Biomarker | phenotype | BEFREE | Our results suggest a critical role of miR-141 in suppressing metastasis of HCC cells by targeting E2F3. | 25142234 | 2014 | ||||
|
0.100 | AlteredExpression | phenotype | BEFREE | Moreover, the decreased miR-141 level was significantly associated with tumor size and TNM stage, as well as lymph node and distant metastasis. | 24013097 | 2013 | ||||
|
0.100 | Biomarker | phenotype | BEFREE | Here, we demonstrate by ectopic expression and gene silencing that the proto-oncogene c-Myb activates the expression of the 5 members of miR200 family (miR200b, miR200a, miR429, miR200c and miR141) that are involved in the control of epithelial-mesenchymal transition (EMT) and metastasis in many types of cancers. | 24067373 | 2013 | ||||
|
0.100 | AlteredExpression | phenotype | BEFREE | The serum miR-141 level was found to be positively correlated with alkaline phosphatase (ALP) level in patients with skeletal metastasis, using Pearson's bivariate correlation test. | 23377530 | 2013 | ||||
|
0.100 | Biomarker | phenotype | BEFREE | The relative concentrations of breast cancer-associated miR10b, miR34a, miR141 and miR155 were measured in the blood serum of 89 patients with primary breast cancer (M0, n = 59) and metastatic disease (M1, n = 30), and 29 healthy women by a TaqMan MicroRNA Assay. | 21047409 | 2010 |