Gene: NEAT1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Furthermore, the regulatory effects of NEAT1 on the proliferation and metastasis of laryngocarcinoma cells were evaluated. 31364125 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE High expression of NEAT1 was significantly associated with TNM stage (P=0.000) and metastasis (P=0.000). 30845377 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE NEAT1 and CDK6 could promote cell proliferation and metastasis of glioma cells and impeded cell apoptosis, whereas miR-139-5p exerted suppressive effects on the biological functions of glioma cells. 30515782 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Up-regulated NEAT1 promotes cell proliferation and metastasis of colorectal cancer both in vitro and in vivo. 30312725 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE The high level of NEAT1 expression can predict the metastasis of lymph node (OR = 3.36, 95% CI = 1.66-6.77, <i>p</i> = .000) and it is a molecular marker of positive lymph node for treatment. 31213091 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Critical roles of NEAT1 in regulation of apoptosis, cell growth and proliferation, invasion and metastasis in several tissues indicate that this lncRNA might be a therapeutic target in various cancers. 30576934 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Our findings indicate a novel mechanism by which ALKBH5 promotes GC invasion and metastasis by demethylating the lncRNA NEAT1. 31290116 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Animal experiments were used to determine the role of NEAT1 in CRC tumorigenicity and metastasis in vivo. 30185232 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Then, in vitro assays revealed that NEAT1 promotes EMT and metastasis by stimulating the inactivation of HIF-2α in HCC. 29091312 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE NEAT1 expression was also related to race (P = 0.025) and distant metastasis (P = 0.002). 30021196 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE In the present study, lncRNA NEAT1 was detected to be significantly upregulated in NSCLC tissues and closely associated with advanced TNM stages, lymph node metastasis, distant metastasis, and poor prognosis. 28762332 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 GeneticVariation phenotype BEFREE Therefore, nuclear-enriched RBP, PTBP3, promotes HCC cell malignant growth and metastasis by regulating the balance of splicing variants (NEAT1_1, NEAT1_2 and miR-612) in HCC. 30068940 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE NEAT1_2 knockdown led to a significant inhibition of growth and metastasis, and induced apoptosis in PTC cells. 29515109 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE <b>Conclusion:</b> LncRNA NEAT1 was up-regulated in osteosarcoma tissue, promoting proliferation and metastasis of osteosarcoma cells. 30123061 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE Taken together, our study reveals a critical epigenetic mechanism underlying NEAT1-mediated metastasis. 29416922 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE CCA cells transfected with shNEAT1 also exhibited reduced metastasis and invasiveness in Transwell assays. 28810932 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE NEAT1 was overexpressed in OS tissues, which positively correlated with tumor size, Enneking stage, and distant metastasis of OS patients. 29654165 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE CCA cells transfected with shNEAT1 also exhibited reduced metastasis and invasiveness in Transwell assays. 29970216 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE lncRNA NEAT1 competes against let-7a to contribute to non-small cell lung cancer proliferation and metastasis. 29864936 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE In addition, we revealed that depression of NEAT1 inhibited OC cells' metastasis and the expression of Rho associated coiled-coil containing protein kinase 1 (ROCK1), which is a metastasis-related gene. 29790629 2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE The clinicopathological parameters analysis further showed that increased expression level of NEAT1 was positively correlated with larger tumor size (odds ratio (OR) = 1.74, 95% CI = 1.26-2.41), lymph node metastasis (OR = 2.29, 95% CI = 1.71-3.06), advanced TNM stage (OR = 3.60, 95% CI = 2.27-5.72), poor tumor differentiation (OR = 2.16, 95% CI = 1.58-2.93), distant metastasis (OR = 3.51, 95% CI = 1.75-7.01), and invasion depth (OR = 1.94, 95% CI = 1.36-2.75). 27926523 2017
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE MTT and Wound Healing assays showed that suppression of lncRNA NEAT1 could lead to decreased proliferation and metastasis in BC cell lines. 28338194 2017
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE We demonstrated that the FOXN3-NEAT1-SIN3A complex promotes EMT and invasion of breast cancer cells in vitro as well as dissemination and metastasis of breast cancer in vivo. 28805661 2017
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 AlteredExpression phenotype BEFREE Furthermore, elevated NEAT1 expression significantly predicted lymph node metastasis (HR: 2.10, 95%CI: 1.32-3.33, P = 0.002) and distant metastasis (HR: 2.80, 95%CI: 1.60-4.91, P = 0.0003) respectively. 29026116 2017
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1 		0.100 Biomarker phenotype BEFREE NEAT1 repressed NPC cell growth, invasion and radiation resistance <i>in vitro</i> and tumor metastasis <i>in vivo</i>. 29050268 2017