Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Therapeutic phenotype CTD_human Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF-1α synthesis, and decreases breast cancer metastasis. 28574600 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Biomarker phenotype CTD_human Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF-1α synthesis, and decreases breast cancer metastasis. 28574600 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.310 Biomarker phenotype BEFREE By using a nanobody as a biological ligand of the human epidermal growth factor 2 receptor (HER2), the active targeting is demonstrated in vitro and in vivo in an experimental tumor model by using darkfield microscopy and photoacoustic imaging. 28152380 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.310 Biomarker phenotype CTD_human Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF-1α synthesis, and decreases breast cancer metastasis. 28574600 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.310 Biomarker phenotype BEFREE However HIF-1α and HIF-2α have contrasting effects on experimental tumor progression. 26262842 2015
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.310 Therapeutic phenotype CTD_human Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment. 24345465 2014
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		0.310 Therapeutic phenotype CTD_human Influence of osteopontin expression on the metastatic growth of CC531 rat colorectal carcinoma cells in rat liver. 21852811 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Therapeutic phenotype CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Biomarker phenotype CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Biomarker phenotype CTD_human HSPG-binding peptide corresponding to the exon 6a-encoded domain of VEGF inhibits tumor growth by blocking angiogenesis in murine model. 20376344 2010
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.310 Biomarker phenotype BEFREE In this study, using the first described C57BL/6 (B6) TRAIL-sensitive experimental tumor models, we have characterized the innate and adaptive immune components involved in the primary rejection phase of an anti-mouse DR5 (mDR5) mAb, MD5-1 in established MC38 colon adenocarcinomas. 20505139 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Therapeutic phenotype CTD_human HSPG-binding peptide corresponding to the exon 6a-encoded domain of VEGF inhibits tumor growth by blocking angiogenesis in murine model. 20376344 2010
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.310 Therapeutic phenotype CTD_human Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells. 17767197 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.310 Biomarker phenotype BEFREE Strategies to block VEGF/VEGFR-2 signaling were successfully used to inhibit experimental tumor growth and indicated that VEGFR-2 is the main signaling VEGF receptor in proliferating tumor endothelium. 15221961 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.310 Biomarker phenotype CTD_human Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission. 14612517 2003
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		0.310 Biomarker phenotype BEFREE Osteopontin (OPN), an integrin-binding, transformation-associated protein, is secreted by tumor cell lines in culture and is associated with increased malignancy in some experimental tumor systems. 8959677 1996
Entrez Id: 406935
Gene Symbol: MIR143
MIR143 		0.300 Therapeutic phenotype CTD_human Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth. 31152816 2019
Entrez Id: 3950
Gene Symbol: LECT2
LECT2 		0.300 Therapeutic phenotype CTD_human Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities. 30453282 2018
Entrez Id: 10550
Gene Symbol: ARL6IP5
ARL6IP5 		0.300 Biomarker phenotype CTD_human JWA deficiency induces malignant transformation of murine embryonic fibroblast cells. 29545876 2018
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7 		0.300 Biomarker phenotype CTD_human Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. 29507229 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.300 Biomarker phenotype CTD_human Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. 29507229 2018
Entrez Id: 574436
Gene Symbol: MIR485
MIR485 		0.300 Biomarker phenotype CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017
Entrez Id: 768212
Gene Symbol: MIR758
MIR758 		0.300 Biomarker phenotype CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017
Entrez Id: 442914
Gene Symbol: MIR369
MIR369 		0.300 Biomarker phenotype CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.300 Biomarker phenotype CTD_human Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer. 28030816 2017