×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
Mutations associated with familial melanoma impair p16INK4 function.
7647780
1995
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children.
26104880
2015
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Haplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families.
11319798
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry.
17171691
2007
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL.
17047042
2006
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds.
9416844
1997
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
Biomarker
group
BEFREE
Hereditary pancreatic carcinoma shows extant phenotypic and genotypic heterogeneity as evidenced by its integral association with a variety of hereditary cancer syndromes inclusive of the familial atypical multiple mole melanoma (FAMMM) syndrome in concert with CDKN2A (p16) germline mutations.
11815963
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
CDKN2A mutations and melanoma risk in the Icelandic population.
18178632
2008
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
Genotype analysis in Hungarian patients with multiple primary melanoma.
24660985
2014
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
CDKN2A germline mutations in individuals with cutaneous malignant melanoma.
17218939
2007
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Analysis of the p16 gene, CDKN2, in 17 Australian melanoma kindreds.
8570179
1995
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds.
7670475
1995
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
Protective effect of copy number polymorphism of glutathione S-transferase T1 gene on melanoma risk in presence of CDKN2A mutations, MC1R variants and host-related phenotypes.
19484507
2009
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Increased prevalence of lung, breast, and pancreatic cancers in addition to melanoma risk in families bearing the cyclin-dependent kinase inhibitor 2A mutation: implications for genetic counseling.
25064638
2014
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
CDKN2A germline splicing mutation affecting both p16(ink4) and p14(arf) RNA processing in a melanoma/neurofibroma kindred.
11433531
2001
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
CDKN2A (p16INK4A) somatic and germline mutations.
8723678
1996
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas.
10398427
1999
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
CDKN2A mutations in melanoma families from Uruguay.
19523171
2009
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families.
10922411
2000
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma.
9916806
1999
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Hereditary p16-Leiden mutation in a patient with multiple head and neck tumors.
12549483
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Multiple neurofibromas as the presenting feature of familial atypical multiple malignant melanoma (FAMMM) syndrome.
23613284
2013
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
The p16INK4a/CDKN2A tumor suppressor and its relatives.
9823374
1998
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
CausalMutation
group
CLINVAR
Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma.
8668202
1996
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.110
GeneticVariation
group
CLINVAR
Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients.
19260062
2009